The primary purpose of this study was to examine the impact of acute highintensity interval Exercise (HIIE) on plasma cfDNA and IL-6 responses in obese and normal-weight subjects. Fifteen subjects (8 obese and 7 normal-weight) were recruited to participate in an acute HIIE protocol. Our results demonstrated a significant elevation across time in plasma cfDNA and IL-6 immediately following acute HIIE, with no difference between obese and normal-weight subjects. Furthermore, cfDNA was not correlated with IL-6 in response to acute HIIE in either group. These findings indicate that the obese state does not further exacerbate the release of acute HIIE-induced inflammatory mediators (cfDNA and IL-6), which suggests that HIIE training may serve as a time-effective exercise strategy to improve obesity-associated inflammation. / Includes bibliography. / Thesis (M.S.)--Florida Atlantic University, 2017. / FAU Electronic Theses and Dissertations Collection

Access to abstract permanently restricted to Ball State community only / Access to thesis permanently restricted to Ball State community only / School of Physical Education, Sport, and Exercise Science

The primary purpose of this study was to investigate the effect of acute high-intensity interval exercise (HIIE) vs. continuous moderate-intensity exercise (CME) on serum CTRP9 and brachial FMD responses in obese and normal-weight subjects. Sixteen participants (9 obese and 7 normal-weight) completed HIIE and CME in a randomized fashion. Our results showed a significant time effect for CTRP9 immediately following acute HIIE and CME in both groups. Furthermore, both significant treatment by time and group by time interactions for FMD were observed following both exercise protocols, with greater CME-induced FMD response in obese subjects than normal-weight subjects. Additionally, a positive correlation in percent change (baseline to peak) between CTRP9 and FMD was observed following acute CME. These findings support acute CME for improvement of endothelial function in obesity. Furthermore, the novel results from this study provide a foundation for additional examination of the mechanisms of exercise-mediated CTRP9 on endothelial function. / Includes bibliography. / Thesis (M.S.)--Florida Atlantic University, 2017. / FAU Electronic Theses and Dissertations Collection