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A Mechanical Fluid Assessment of Anatomical Models of the Total Cavopulmonary Connection (TCPC)de Julien de Zelicourt, Diane Alicia 09 December 2004 (has links)
BACKGROUND: Understanding the hemodynamics of the total cavopulmonary connection (TCPC) may lead to further optimization of the connection design and surgical planning, which in turn may lead to improved surgical outcome. While most experimental and numerical investigations have mainly focused on somewhat simplified geometries, the investigation of the flow field of true TCPC configurations is necessary for a true understanding.
METHODS: This study details a manufacturing methodology yielding more accurate in vitro models that would provide a better understanding of the TCPC hemodynamics and adequate data for the validation of anatomical CFD simulations. This approach is illustrated on two different TCPC templates: an intra-atrial TCPC with a single superior vena cava (SVC) and a bilateral SVC with an extra-cardiac conduit. Power loss, flow visualization, digital particle image velocimetry (DPIV) flow measurements as well as computational fluid dynamics simulations are performed to characterize the anatomic flow structure. Additional parametric glass models of the TCPC were manufactured to help understand the fluid dynamics of the anatomical models and support the computational model validation effort.
RESULTS/CONCLUSIONS: Both anatomic configurations revealed very different fluid dynamics underlining once again the need for at least one comprehensive experimental campaign per TCPC template for a good understanding of the flow phenomena. The absence of caval offset in the anatomical intra-atrial model resulted in important flow turbulence, which was enhanced by the large connection area and yielded high pressure drops and power losses. On the other hand, the bilateral SVC, which featured a smooth extra-cardiac conduit and wider vessels, led to power losses that were one order of magnitude lower than those of the anatomic intra-atrial model and a smooth flow field with lower levels of instability. The simplified glass models demonstrated that the diameter of the connecting vessels and of the pulmonary arteries in particular, was a parameter of prime importance.
Finally, this study also reports on a combined experimental and numerical validation methodology, suggesting a cautious approach for the straightforward use of available CFD tools and pointing out the need for developing high resolution CFD techniques specifically tailored to tackle the complexities of cardiovascular flows.
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Quantification and Analysis of the Geometric Parameters of the Total Cavo Pulmonary Connection Using a Skeletonization ApproachKrishnankuttyRema, Resmi 24 August 2007 (has links)
The Fontan repair is a three-stage palliative surgical procedure for single ventricle congenital heart diseases, ultimately resulting in the right heart bypass. This is accomplished by routing the systemic venous return directly to the lungs. Although this procedure reduces the mortality rate, its long-term outcome is still considered far from optimal. Over the years several modifications have been suggested, ultimately leading to the total cavopulmonary connection (TCPC), which is the current procedure of choice. A better understanding of the hemodynamics in the TCPC is critical for further optimization of the TCPC design and surgical planning, which may lead to improved surgical outcome. Recent experimental and numerical studies have focused on characterizing the fluid dynamics of the TCPC but to date no study has attempted to relate the geometry of the TCPC anatomies with their hemodynamic parameters.
The present study therefore proposes to quantify the complex geometrical characteristics of patient-specific TCPC anatomies and correlate these characteristics with their hemodynamic efficiency. A technique using skeletonization approach is thus developed to achieve this goal. The centerline approximation of the TCPC geometry is used to extract main geometric parameters such as vessel area, curvature and offset. The developed methodology is then applied to characterize the shape of various TCPC templates including extra-cardiac (EC) and intra-atrial (IA) TCPCs, TCPCs with bilateral Superior Vena Cavae and geometries before the third stage. The obtained geometric parameters are then related to the TCPC hemodynamics, particularly to the power loss.
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