The secure transportation of food via trucks within the supply chain is a pivotal aspect of ensuring food safety and defense, necessitating the seamless integration of advanced security control processes and systems. This study primarily investigates how the integrated use of Industry 4.0 (4IR) technologies, such as AI, IoT, and Blockchain, alongside ISO standards like ISO 28001 and ISO 22000, in trucking management systems for food transport influences the confidence of supply chain professionals in ensuring that food products remain safe and untampered with during truck transportation. To ensure the robustness of our survey, a two-round Delphi study involving 10 experts in supply chain management was conducted to validate the survey questions concerning truck security in food transportation. Following this validation, the survey was disseminated across several LinkedIn groups focused on food safety, food transportation, and supply chain management. A total of 55 responses were collected and analyzed. The analysis revealed that seal integrity was considered the most critical aspect of truck security, followed by concerns regarding cabin weight changes and cabin temperature. Conversely, the accuracy of driver records and the number of stops were deemed less significant. These insights facilitated the development of a confidence assessment model, where the confidence rating ��=��(����)+��(������)+��(����)+��(����)+��(������), quantifies the impact of Legacy Controls (LC), Internet of Things (IoT), Artificial Intelligence (AI), Blockchain (BC), and ISO Standards (ISO) in enhancing the security of food transport. The study's findings provide a foundational framework and a critical tool for supply chain professionals, empowering them to make informed decisions on security measures and compliance strategies, thereby ensuring food safety. It also contributes to advancing management practices, integrating industrial engineering principles with emerging technologies, and deepening our understanding of their practical application in food transportation security.