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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Fabrication and Characterisation of iontronic micropipette

Hamrefors, Henrik January 2022 (has links)
The biological translation between biological and electrical signals have inspired scientists over the last decade and has opened new way of therapeutics. The group of Bioelectronics at the Laboratory of organic electronics (LOE) develops systems that utilizes this translation to reduce the gap between electronics and biology. A known example of devices that does this are called iontronic delivery devices. These devices allow very specific transport and delivery of charged compounds. The most basic iontronic delivery device is the organic electronic ion pump (OEIP). The OEIP have been developed and fabricated into many variations, for example the iontronic micropipette which is a device that has been developed at LOE. In this project, the fabrication and characterization of the iontronic micropipette have been developed to find fabrication parameters that generates stable, high performing and reproduceable devices together with good and reproduceable characterization protocols. The iontronic micropipette is fabricated in a cleanroom and characterized in two steps, optically in a microscope and then electrically by transporting ions through the membrane. Two different membrane materials were tested, 2- acrylamido-2-methylpropane sulfonic acid (AMPSA) and Hyperbranched polyglycerols (HPG). The results that were obtained from the fabrication of the AMPSA showed a reproducibility between many devices, but many AMPSA device broke during the fabrication so the protocol for the AMPSA still need improvement. Regarding the A-HPG fabrication, the results were much more positive and the yield from the fabrication were sufficient. The results that were obtained in the characterization of the AMPSA device showed that these devices had a very equal resistance between the device from the same batch. For the A-HPG, it was a much larger spread in the resistance between the device but the resistance were still much lower than for the AMPSA which is more preferable for most applications on living cells. / <p>Examensarbetet är utfört vid Institutionen för teknik och naturvetenskap (ITN) vid Tekniska fakulteten, Linköpings universitet</p>

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