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Influence of metal chelate formation on pharmacokinetics/pharmacodynamics of ciprofloxacin.January 1998 (has links)
by Wong Yin Kwan. / Thesis (M.Phil.)--Chinese University of Hong Kong, 1998. / Includes bibliographical references (leaves 105-115). / Abstract also in Chinese. / Title page --- p.i / Acknowledgements --- p.ii / Table of contents --- p.iii / Abbreviations --- p.v / Abstract --- p.vi / 摘要 --- p.xi / Chapter Chapter 1 --- Introduction --- p.1 / Chapter Chapter 2 --- Assay Development for Ciprofloxacin / Chapter 2.1 --- Introduction --- p.23 / Chapter 2.2 --- HPLC Assay --- p.24 / Chapter 2.3 --- Microbiological Assay --- p.29 / Chapter 2.4 --- Discussion --- p.30 / Chapter Chapter 3 --- The Effects of Oral Ferrous Sulfate on Pharmacokinetics and Pharmacodynamics of Intravenous Ciprofloxacin / Chapter 3.1 --- Introduction --- p.43 / Chapter 3.2 --- Materials and Methods --- p.45 / Chapter 3.3 --- Results --- p.49 / Chapter 3.4 --- Discussion --- p.51 / Chapter Chapter 4 --- The Effects of Oral Ferrous Sulfate on Pharmacokinetics and Pharmacodynamics of Oral Ciprofloxacin / Chapter 4.1 --- Introduction --- p.61 / Chapter 4.2 --- Materials and Methods --- p.62 / Chapter 4.3 --- Results --- p.66 / Chapter 4.4 --- Discussion --- p.68 / Chapter Chapter 5 --- Influence of Mineral Rich Traditional Chinese Medicines on the Pharmacokinetics of Oral Ciprofloxacin / Chapter 5.1 --- Introduction --- p.77 / Chapter 5.2 --- Materials and Methods --- p.81 / Chapter 5.3 --- Results --- p.85 / Chapter 5.4 --- Discussion --- p.86 / Chapter Chapter 6 --- General Conclusion --- p.98 / References --- p.105
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