Numerical simulations of fluid-structure interaction (FSI) problems were performed in an effort to verify and validate a commercially available FSI tool. This tool uses an iterative partitioned coupling scheme between CD-adapco's STAR-CCM+ finite volume fluid solver and Simulia's Abaqus finite element structural solver to simulate the FSI response of a system. Preliminary verification and validation work (VandV) was carried out to understand the numerical behavior of the codes individually and together as a FSI tool. Verification and Validation work that was completed included code order verification of the respective fluid and structural solvers with Couette-Pouiselle flow and Euler-Bernoulli beam theory. These results confirmed the 2nd order accuracy of the spatial discretizations used. Following that, a mixture of solution verifications and model calibrations was performed with the inclusion of the physics models implemented in the solution of the FSI problems. Solution verifications were completed for fluid and structural stand-alone models as well as for the coupled FSI solutions. These results re-confirmed the spatial order of accuracy but for more complex flows and physics models as well as the order of accuracy of the temporal discretizations. In lieu of a good material definition, model calibration is performed to reproduce the experimental results. This work used model calibration for both instances of hyperelastic materials which were presented in the literature as validation cases because these materials were defined as linear elastic. Calibrated, three dimensional models of the bow seal on the University of Michigan bow seal test platform showed the ability to reproduce the experimental results qualitatively through averaging of the forces and seal displacements. These simulations represent the only current 3D results for this case. One significant result of this study is the ability to visualize the flow around the seal and to directly measure the seal resistances at varying cushion pressures, seal immersions, forward speeds, and different seal materials. SES design analysis could greatly benefit from the inclusion of flexible seals in simulations, and this work is a positive step in that direction. In future work, the inclusion of more complex seal geometries and contact will further enhance the capability of this tool. / Ph. D.