The lower Da-An River in western Taiwan was uplifted ~10 during the 1999 Mw 7.6 Chi-Chi earthquake, resulting in a 20- to 30-m-deep bedrock gorge. However, the amount of coseismic displacement along the channel bed does not fully explain the resulting bedrock channel incision. Using a series of aerial photographs, digital terrain models (DEM), and real-time kinematic global positioning system (RTK GPS) surveys, we characterized knickpoint retreat and fluvial incision in the Da-An River gorge. We also analyzed discharge and precipitation data and collected measurements of rock strength and joint plane orientations to understand the climatic, lithological, and structural influence on the evolution of the actively incising gorge. Two stages of fluvial incision and knickpoint migration are identified in the gorge following surface uplift during the Chi-Chi earthquake. From 1999 to 2004, 3 to 5 m of alluvium was removed from the channel bed, followed by 3 to 4 m of bedrock channel incision. The knickpoint generated immediately after the earthquake stayed where the uplift occurred at this time. Since 2005, the channel bed has lowered rapidly with local incision rate as high as 15 m/yr in terms of knickpoint migration. The average knickpoint migration rate over the period 2005 to 2009 was 238 m/yr; total upstream migration from the location of knickpoint formation was 1190 m. While tectonic uplift formed the knickpoint and set the stage for channel incision, climate played a critical role in accelerating the fluvial response to coseismic displacement. More than 20 m of bedrock channel incision and 1180 m knickpoint migration occurred during the post-2004 typhoon seasons (May-October). Based on repeat surveys of the Da-An River longitudinal profile and analysis of precipitation and discharge data, we suggest that a discharge threshold of 1200 to 2600 m³/s is required to initiate upstream knickpoint migration. However, once the threshold is exceeded, bedding dip becomes the primary control on rates and patterns of knickpoint propagation. Rotation occurred in a hinge zone where the bedding dips change from horizontal to upstream-dipping, while replacement was observed in the strata dipping upstream. The highest knickpoint migration rates (> 300 m/yr) were recorded in flat-lying, horizontal strata (< 10º) where parallel retreat was the dominate process. Overall, the knickpoint propagation followed the process of replacement behavior, in which the height of knickpoint decreases while migrating upstream. Thus, while tectonic processes set the initial conditions for knickpoint propagation in the Da-An River, the response time of the fluvial system to this forcing is strongly dependent on climate and local structure.