Human’s energy demand is growing and there is a necessity to solve questions of sustainable energetics, such as security of energy supply, energy efficiency and environment protection. Possible way of the solution of these problems is new and more efficient technologies and new energy sources. Fuel cells are one of the developing and environmentally clean technologies. This master’s report is dealing with cogeneration technologies and only fuel cells are analyzed thoroughly. Most usable type of fuel cells for decentralized power and heat generation is identified and its operating principles and properties are analyzed. Advantages and disadvantages of solid oxide fuel cells are given. Power of the fuel cell is chosen in the particular case, when energy demand of building complex of the hospital is analyzed. The fuel cell is integrated into the energy supply system with other equipment. There are made several alternatives to estimate the operation of the system technologically and economically. The simple pay back period and the net present value are used to estimate economical benefit of the system, when prices of energetic sources and fuel cells are varied. Finally, academic knowledge and calculation results are summarized and conclusions of the final report are given.