The nuclear waste problem is defined and analyzed from a systems engineering viewpoint. Problem magnitude and systems context are discussed. Requirements for a waste repository are presented and the current progress of the repository is noted. The Department of Energy's waste disposal system including repository site selection, monitored retrievable storage facility, and waste transportation system is analyzed. A description of nuclear fuel reprocessing is given. The potential benefits and risks of reprocessing are addressed including economic feasibility and environmental issues. A framework for systems analysis of the problem is presented. Four recommendations for further systems analysis are presented: 1. An unbiased systems analysis of the Yucca Mountain proposed repository including indirect political, social and economic aspects. 2. A systems engineering backing of the monitored retrievable storage facility 3. Development of rail transportation guidelines for nuclear waste 4. An economic analysis of the feasibility of spent fuel reprocessing to include indirect costs / Master of Engineering