A field investigation of the pollution existing in the Roanoke River within the Roanoke Metropolitan district was carried out from June, 1940 to May, 1941 by various departments of the Virginia Polytechnic Institute with the material aid of several other interested groups. Studies of the chemical and bacteriological conditions, and of the microscopic life existing in the stream were made by P. H. McGauhey and H. F. Eich, of the Department of Civil Engineering. The invertebrate and vertebrate life of the stream, as well as the toxicity of viscose wastes to fishes, was investigated by H. W. Jackson and Croswell Henderson, of the Department of Biology. Monthly mineral analyses of water were made by F. H. Fish and others of the Department of Chemistry, and data relative to certain industrial wastes were furnished by R. A. Fisher and Dudley Thompson, of the Department of Chemical Engineering. / Master of Science