This dissertation examines emergent forms of digitally enabled boundary-spanning by considering the within- and cross-field interactions developed by LGBTQIA* organisations on social media. Within scholarship on collective actors characterised by strong collective identities, LGBTQIA* collective action fields have been conventionally found to be rather fragmented and polarised, as well as isolated from other fields. Nonetheless, recent studies have shown evidence of the emergence of cooperative and solidarity efforts by LGBTQIA* actors, suggesting that such LGBTQIA* organisations may actively engage in crossing categorical boundaries and overcoming differences in the attempt to achieve social change. Within this framework, information and communication technologies (ICTs) may provide LGBTQIA* communities with spaces to converge, share experiences, and articulate politicised identities also through the connection with other collective actors. Despite these findings, we currently lack a systematic understanding of the extent to which LGBTQIA* collective actors span field boundaries through the development of digitally enabled interactions, of how such ties evolve over time, and on the circumstances that may favour or inhibit their emergence and duration. Furthermore, the role of ICTs in supporting the emergence of boundary-spanning processes has so far been rather understudied. This dissertation addresses these concerns by conducting a mixed-method comparative research on LGBTQIA* actors based in Madrid and Milan. In particular, it focuses on different types of interactions (mentioning, sharing, and promoting collective action events) developed by such organisations on their Facebook public pages during the 2011-2020 decade. To examine the role of both cultural patterns (collective identities and framing strategies) and structural circumstances (political opportunities and threats), this study combines network and text data, analysed through social network and frame analysis. The findings provided by this research show that Spanish and Italian LGBTQIA* organisations increasingly crossed categorical boundaries through social media between 2011 and 2020, thus suggesting that ICTs do play a role in sustaining boundary-spanning processes. Moreover, they find that collective framing and networking are inextricably entangled, and hence contribute to shedding light on both symbolic and behavioural dimensions of digitally enabled boundary-spanning. To conclude, they show that actors embedded in different socio-political contexts engage in networking and framing, thus emphasising the role of contextual opportunities and threats in moderating the nexus between ICTs and boundary-spanning, as well as between framing and networking. This dissertation contributes to both social movement literature and gender studies. On the one hand, by shedding light on emergent forms of boundary-spanning processes enabled by ICTs, it not only contributes to examining the role of ICTs in empowering marginalised communities, but also further elaborates the entanglement between digital, hybrid, and on-the-ground collective actions. On the other hand, by systematically investigating an emerging phenomenon over time and across contexts, it contributes to generating knowledge on the circumstances encouraging collective actors to overcome differences and cooperate. Understanding this is of utmost importance, since cooperative relations provide collective actors with additional and diverse resources and experiences, as well as political legitimation, to resist processes of democratic erosion and achieve social change.