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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
61

Development and application of sequencing based typing for HLA class I related genes

Day, Sarinder January 2000 (has links)
No description available.
62

The induction of immune responses in the murine small intestine

Harper, Helen Margaret January 1995 (has links)
No description available.
63

Characterisation of non-lyphoid cells in the small intestinal lamina propria of the rat and the pig

Kambarage, D. M. January 1991 (has links)
No description available.
64

Identification of membrane components associated with the expression of the Rhesus D antigen on human red cells

Wilson, C. F. January 1985 (has links)
No description available.
65

Blood-group antigen expression in normal and neoplastic urothelium and prostate : Can changes in blood-group antigen expression indicate the future behaviour of transitional cell cancer of the bladder

Abel, P. D. January 1986 (has links)
No description available.
66

Establishment and use of HSV-2 type-specific serological assays to assess the antibody status of populations attending antenatal and genito-urinary medicine clinics

Azhar, Esam Ibraheem A. January 1999 (has links)
No description available.
67

Analysis of the mouse CD4 T cell repertoire by high efficiency cloning

Jones, Sian Helen January 1992 (has links)
No description available.
68

Minimal residual disease in acute leukaemia by quantitative flow cytometry

Farahat, Nahla Mohamed Gamal January 1996 (has links)
No description available.
69

Characterization of T lymphocyte antigens

Mallett, Susan January 1991 (has links)
No description available.
70

Influence of 2 fluorohistidine on pore formation in the anthrax protective antigen

Zhou, Haiying 07 1900 (has links)
Bacillus anthracis secretes a toxin which consists of three proteins that is the cause of the anthrax disease symptoms leading to death. They are called the protective antigen (PA), edema factor (EF) and lethal factor (LF). The three proteins self-assemble into toxic complexes after PA binding to its receptors present on host cells. The toxin receptor complexes are then internalized and acidic endosomal pH triggers pore formation by PA and translocation of the LF and/or EF into the cytosol. In this study, we labeled PA with 2-fluorohistidine, an analog of histidine with a dramatically reduced side-chain pKa, in order to test the hypothesis that histidine protonation triggers the pH dependent change from a prepore to a pore. We have analyzed its functional properties. It can be cut by furin or trypsin and it can also bind with one of its receptor, the VWA domain of CMG2 and form a heptamer as wild type PA. However, the pore formation can be blocked by this labeled protein when bound to CMG2. Independent experiments show that 2F-His labeled PA can also block translocation. By modifying the protein with 2F-His, we show that histidine in PA and CMG2 does not play as a pH-sensitive trigger in the pore formation process. We provide hypotheses for these findings. / Thesis (M.S.)--Wichita State University, College of Liberal Arts and Sciences, Dept. of Chemistry. / "July 2006." / Includes bibliographic references (leaves 96-102).

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