Abstract: This thesis is concerned with the acquisition of body signals using a sampling system. A typical application is the recording of the electrocardiogram (ECG). It is proposed to sample the input signal at different rates, depending on the momentary signal content. If the input signal has large voltage variation, it is sampled at a high rate. During periods of small variation, the signal is sampled at a lower frequency to save both memory and power. An analog controller to control the clock rate is proposed and implemented. The analog controller decides the sample frequency (high rate or low rate) depending on the input signal. The analysis of the proposed system is presented in this thesis. Furthermore, a working prototype is implemented using discrete components on a PCB. The measured results show a significant reduction in the average sample frequency and data rate of 50% and 35%, respectively. Finally, the critical analog circuit blocks of the system suitable for integration on chip are proposed and implemented in a 0.35£gm CMOS process. Measured results are reported to confirm the functionality of the blocks.