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Leptin action on ovulation and leptin receptors across the rat oestrous cycle /Duggal, Priya S. January 2001 (has links) (PDF)
Thesis (Ph.D.) -- University of Adelaide, Dept. of Obstetrics and Gynaecology, 2001. / Bibliography: leaves [124-153].
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B lymphocyte development and function in leptin receptor-deficient miceXu, Jialin, 徐嘉林 January 2005 (has links)
published_or_final_version / Medical Sciences / Master / Master of Medical Sciences
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Expression and regulation of leptin receptor in human and mouse oviductMak, Amy., 麥安美. January 2006 (has links)
published_or_final_version / Medical Sciences / Master / Master of Medical Sciences
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LEPTIN RECEPTORS IN CAVEOLAE: REGULATION OF LIPOLYSIS IN 3T3-L1 ADIPOCYTESChikani, Gentle P. 01 January 2004 (has links)
The present study has tested the hypothesis that leptin receptors are localized in caveolae and that caveolae are involved in the leptin-induced stimulation of lipolysis in 3T3-L1 adipocytes. Leptin, a peptide hormone, is secreted primarily by adipocytes and has been postulated to regulate food intake and energy expenditure via hypothalamic-mediated effects. Exposure to leptin increases the lipolytic activity in 3T3-L1 adipocytes. We isolated caveolae from 3T3-L1 adipocytes using a detergent free sucrose gradient centrifugation method. Leptin receptors were localized in the same gradient fraction as caveolin-1. Confocal microscopic studies demonstrated the colocalization of leptin receptors with caveolin-1 in the plasma membrane, indicating distribution of leptin receptors in the caveolae. We disrupted caveolae by treating cells with methyl--cyclodextrin and found that leptin induced lipolytic activity was reduced after caveolae disruption, indicating an important role of caveolae in the signaling mechanism of leptin.
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Leptin action on ovulation and leptin receptors across the rat oestrous cycleDuggal, Priya S. (Priya Sunanda) January 2001 (has links) (PDF)
Bibliography: leaves [124-153]
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Leptin action on ovulation and leptin receptors across the rat oestrous cycle / Priya S. Duggal.Duggal, Priya S. (Priya Sunanda) January 2001 (has links)
Bibliography: leaves [124-153] / x, 123 leaves : ill. (chiefly col.) ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Thesis (Ph.D.)--University of Adelaide, Dept. of Obstetrics and Gynaecology, 2001
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