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no / This article presents a review of key issues around caring for people in the last hours and days of life. The aim is that community nurses will be able to support patients and families, and to provide and explain decisions and interventions to promote comfort and dignity based on current evidence.

Se desarrolló una tesis de Vivienda social en Barrios Altos. La vivienda social, es residencia de bajo presupuesto, económica en uso y mantenimiento destinada a familias de menores recursos. En este trabajo, se investigo la posibilidad de proponer un módulo de vivienda productiva o vivienda taller, que combine la vida con el trabajo en un mismo lugar. Se presentaron las motivaciones para investigar y proponer dicho proyecto en la capital, siendo el más importante solucionar el déficit habitacional existente y mejorar las condiciones de calidad de vida. Se presenta la investigación de proyectos referenciales nacionales e internacionales de la tipología (vivienda masiva), con los cuales se logra concluir con lineamientos formales, funcionales y tecnológicos necesarios para poder desarrollar el proyecto arquitectónico. Así mismo, se realizó un análisis sobre el carácter flexible en distintos proyectos arquitectónicos importantes, así como también en la teoría, ya que el proyecto enfatizará en esta característica para logar incluir vivienda y trabajo, para poder adaptarse a los distintos tipos de familias y su indudable carácter variable, y satisfacer necesidades actuales de adaptabilidad de uso. Además, se estudia sobre las condiciones del lugar y sobre las tipologías de vivienda existentes en la zona, en donde priman las viviendas de tipo quinta, callejones y casas patio, habitadas ahora por múltiples familias o combinando usos comerciales, en estas tres, resalta el sentido de la comunidad y pertenencia, cualidades que son importantes conservar a la hora de proponer el proyecto arquitectónico. / A thesis on Social Housing was developed in Barrios Altos. Social housing is low-budget residence, economic in use and maintenance, for families with fewer resources. In this work, it was researched the possibility of proposing a housing module that combines housing and workshop in the same place. The motivations for researching and proposing such project in the capital were presented, the most important being to solve the existing housing deficit and improve quality of life conditions in this area. National and international Housing projects were presented, with which it is possible to conclude with formal, functional and technological guidelines necessary to be able to develop an architectural project. Moreover, an analysis was carried out on the flexible character in different important architectural projects, as well as theory regarding this subject, since the project will emphasize in flexibility to include both housing and work in one module, also, to be able to adapt to different types of families and their undoubtedly variable character (needs and number of members), and satisfy current needs of adaptability of use. In addition, conditions of Barrios Altos were studied, as well as existing housing typologies in the area, where “quintas”, “callejones” and Patio houses, now inhabited by multiple families. In all of these, the sense of community and belonging is emphasized, such qualities are important to preserve when proposing the architectural project. / Tesis

Although the female menopause has been extensively characterized as a well-defined symptomatic state of oestrogen deficiency, which responds relatively well to oestrogen replacement therapy, the symptomatic state of androgen deficiency in men is poorly defined and uncertainty exists whether it responds to testosterone replacement. It has been proposed that hypothalamic-pituitary-testicular (HPT)-axis function (responsible for the production of androgens) and regulation could be viewed as a ‘barometer’ of health status in older men and that potential alterations in HPT-axis function and regulation reflect subclinical and clinical deficits in function and health, which may result in an aged phenotype of human health and disease in older men. The HPT-axis constitutes a well-defined, tractable, clinically-relevant, biological system, which may permit insight into the mechanisms underlying the expression of ageing-related phenotypes of human health and disease. By using a different lens – such as the genetic background; the compensatory responses within the HPT-axis; the syndromes of androgen deficiency; the ethnic background of an individual or the life course trajectory of function and health from conception into older age – to magnify potential dysregulation in the HPT-axis will it be possible to visualize and understand the phenotypic expression of human male ageing as a gradient of functional and health outcomes. This will allow for a better understanding of the physiological mechanics underlying symptomatic expression of dysregulation in the HPT-axis.