Global ETD Search

1	Lack of sexual dimorphism in effects of local anesthetics Petishnok, Laura Catherine 03 July 2018 (has links) Research suggests biological sex differences may affect pain perception, however the difference in analgesic tolerance between male and females not been extensively studied. Therefore, here we studied the response of male and female Sprague-Dawley rats to prolonged duration local anesthetics; including conventional amino-amide anesthetics (bupivacaine), site 1 sodium channel blockers (tetrodotoxin) and a prolonged duration liposomal formulation (Exparel). This study examined the incidence and duration of sensory and motor blockade; systemic side effects, as well as local neurotoxicity and myotoxicity in both male and female rodents in an in vivo model of sciatic nerve blockade. The data collected does not indicate a sexual dimorphism among the agents studied. / 2019-07-03T00:00:00Z Medicine Bupivacaine Liposomal bupivacaine Local anesthetics Sexual dimorphism Tetrodotoxin
2	A comparison of liposomal bupivacaine and bupivacaine for pain control in untreated symptomatic vital teeth Bultema, Kristy 14 October 2015 (has links) No description available. Dentistry liposomal bupivacaine bupivacaine HCl pain control pain tooth teeth numbness anesthesia anesthetic symptomatic irreversible pulpitis symptomatic vital teeth untreated endodontics vital