The objective of this work is to enhance the awareness of the indoor propagation behaviour, by a set of investigations including simulations and measurements. These investigations include indoor propagation behaviour, local mean power estimation, proposing new indoor path loss model and introducing a case study on 60 GHz propagation in indoor environments using ray tracing and measurements. A summary of propagation mechanisms and manifestations in the indoor environment is presented. This comprises the indoor localization techniques using channel parameters in terms of angle of arrival (AOA), time of arrival (TOA) and received signal strength (RSS). Different models of path loss, shadowing and fast fading mechanisms are explored. The concept of MIMO channels is studied using many types of deterministic channel modelling such as Finite Difference Time Domain, Ray tracing and Dominant path model. A comprehensive study on estimating local average of the received signal strength (RSS) for indoor multipath propagation is conducted. The effect of the required number of the RSS data and their Euclidian distances between the neighbours samples are investigated over 1D, 2D and 3D configurations. It was found that the effect of fast fading was reduced sufficiently using 2D horizontal’s arrangement with larger spacing configuration. A modified indoor path loss prediction model is presented namely effective wall loss model (EWLM). The modified model with wall correction factors is compared to other indoor path loss prediction models using simulation data (for 2.4, 5, 28, 60 and 73.5 GHz) and real-time measurements (for 2.4 and 5 GHz). Different operating frequencies and antenna polarizations are considered to verify the observations. In the simulation part, EWLM shows the best performance among other models. Similar observations were recorded from the experimental results. Finally, a detailed study on indoor propagation environment at 60 GHz is conducted. The study is supported by Line of Sight (LoS) and Non-LoS measurements data. The results were compared to the simulated ones using Wireless-InSite ray tracing software. Several experiments have confirmed the reliability of the modelling process based on adjusted material properties values from measurements.