Logistics managers work to create practices that reduce technostress, which is associated with diminished productivity in supply chain management. The purpose of this multiple case study was to explore the mitigation strategies that logistics managers at distribution centers used to reduce technostress with their employees in the Los Angeles County, California area. The conceptual framework included in this study was the sociotechnical systems theory. Semistructured interviews were conducted with 6 logistics managers from large distribution centers who implemented mitigation strategies that demonstrably reduced technostress with their employees. Public documents and physical artifacts reviewed in this study included productivity assessment tools, information and communication technology system training materials, technostress mitigation instruments, and information from technological devices. Data were analyzed through a process of pattern matching, cross-case synthesis, and systematic text condensation. The findings included 6 themes: reliance on internal information technology experts; hiring temporary experts; maintaining communication and training; using time management skills and organizing priorities; identification and understanding of employee differences; and implementing well-being, fitness, and health programs. These findings could contribute to positive social change by providing logistics managers with strategies to reduce technostress, which could lead to improved employee well-being, better work conditions, and increased productivity for greater company profitability that could produce a more thriving and prosperous community.