The purpose of this study was to determine the effects of short-term (14d) unilateral leg immobilization using a simple knee brace (60° flexion)/crutchmediated model on muscle function and morphology in men (M, N=13) and women (W, N=14). Isometric and isokinetic (concentric SLOW, 0.52 rad•s-1 and FAST, 5.24 rad•s-1) knee extensor peak torque was determined at three time points (PRE, DAY -2, and DAY -14). At the same time points, magnetic resonance imaging was used to measure the cross-sectional area of the quadriceps femoris and DEXA scanning was used to calculate leg lean mass. Muscle biopsies were taken from vastus lateralis at PRE and DAY-14 for myosin ATPase and myosin heavy chain analysh Women showed greater decreases (PRE vs. DAY-14) compared to men in specific strength (N•cm-2) for isometric (M=3.1±13.3, W=17.1±15.9%; p= 0.055, [mean±SD]) and concentric SLOW (M=4.7±11.3, W=16.6±18.4%; p<0.05) contractions. There were no immobilization-induced sex-specific differences in the decrease in quadriceps femoris cross-sectional area (M=5.7±5.0, W=5.9±:5.2%) or leg lean mass (M=3.7±4.2, W=2.7±2.8%). There were no fiber type transformations, and the decrease in Type I (M=4.8±5.0, W=5.9±3.4%), IIa (M=7.9±9.9, W=8.8±8.0%) and Ilx (M=10.7±10.8, W=10.8±12.1 %) fiber areas was similar between sexes. These findings indicate that immobilization-indt: ced loss of knee extensor muscle strength is greater in women compared tc men in spite of a similar extent of atrophy at the myofiber and whole muscle levels after only 14d of unilateral leg immobilization. Furthermore, we have described an effective and safe method of knee immobilization that results in significant reductions in quadriceps muscle strength and fiber size. / Thesis / Master of Science (MS)

This paper presents the design of an underactuated lower body exoskeleton to assist with walking. It reduces the amount of bodyweight going through the user's leg by providing a supporting force to the user that is engaged and disengaged depending on the stage of the gait cycle the user is in. It is engaged when the leg is in stance, effectively pushing between the ball of the foot and the hips, and is disengaged during leg swing. This support force is provided by a linear actuator on each leg that consists of a compression spring, ball screw, and motor. It works by having the motor turn the ball screw, which moves a metal plate to either compress or decompress the spring. The actuator is designed to always be able to extend, to avoid limiting the user's motion. The spring is disengaged while the leg is in swing in order to reduce any impedance to the user's natural stride. The exoskeleton is also designed to minimize any range of motion limitations to reduce its restrictiveness. The exoskeleton was found to be able to provide 19 lbs (85 N) of support to the user per leg. / Master of Science / Exoskeletons are external devices worn to assist the user's natural movement or strength. This paper outlines the design of an exoskeleton that assists the user in walking by providing a supporting force on any leg that the user's weight is on. This effectively reduces the load on the user's legs, which could help reduce leg strain and fatigue. The exoskeleton releases this force when weight is removed from the leg to allow the user to easily swing their leg forward to step. The exoskeleton was designed to minimize limitations to the range of motion of the leg joints while walking, squatting, or sitting to ensure that the exoskeleton did not feel restricting or uncomfortable. Testing revealed that the exoskeleton was able to provide a supporting force of approximately 19 lbs (85 N) to the user per leg and met all the joint range of motion requirements to avoid restrictiveness.

An underactuated exoskeleton design for walking assistance is presented and evaluated. The exoskeleton uses one motor per leg and makes use of a pantograph to reduce the overall profile and allow the exoskeleton to closely follow the shape of the user's leg. Support is provided between the ball of the user's foot and their waist by compressing a spring in parallel with the user's leg during Stance Phase. The exoskeleton has a mass of 14.0 kg (30.8 lbs) and was tested up to a supplied spring force of 323.6 N (72.75 lbf) which equates to around 161.8 N (36.38 lbf) of assistive force at the waist. Range of motion tests showed minimal restriction at the knee and ankle, but some restriction of the hip. Human subject experiments using a simple gait detection method based on GRF at walking speeds from 0.45 m/s to 1.12 m/s (1.0 mph to 2.5 mph) were performed and showed an increase in the time between actual heel strike and predicted heel strike of approximately 0.05 seconds to 0.1 seconds. Lastly, calculations are presented examining the effect of exoskeleton assistance on the biological joint moments and optimizing the actuator design to reduce power consumption. The actual performance of the exoskeleton is compared with the calculations based on the joint angles during a typical walking cycle. / Master of Science / A design for an exoskeleton capable of providing walking assistance without requiring a motor for every joint is presented and evaluated. The exoskeleton uses one motor per leg and makes use of a pantograph to reduce the required size and allow the exoskeleton to closely follow the shape of the user's leg. Support is provided between the ball of the user's foot and their waist by compressing a spring attached beside the user's leg while the user's foot is on the ground. The exoskeleton weighs 14.0 kg (30.8 lbs) and was tested up to a supplied spring force of 323.6 N (72.75 lbf) which equates to around 161.8 N (36.38 lbf) of assistive force at the waist. Range of motion tests showed minimal restriction at the knee and ankle, but some at the hip. Testing with a human participant using a simple method for determining when to apply support and remove it based on the forces measured at the user's foot were performed at walking speeds of 0.45 m/s to 1.12 m/s (1.0 mph to 2.5 mph). These tests showed an increase in the time between when the heel of the foot initially hits the ground and when the exoskeleton code determined that it occurred of approximately 0.05 seconds to 0.1 seconds. Lastly, calculations are presented examining how exoskeleton assistance affects what is felt at the joints of the user and determining what spring stiffness would best reduce the power required from the motors. The actual performance of the exoskeleton is compared with the calculations based on the joint angles during normal human walking.

In 2021, over three and a half million women entered the postpartum period in the United States [1]. Despite their prevalence, postpartum health is a largely overlooked area. After delivery, 25% of women within this population experience lumbopelvic or pelvic pain during the typical postpartum period [3], up to 8 weeks post-delivery, and research has found these women may continue to experience pain years after delivery [4]. Persistent pelvic region pain in postpartum women may result in lower limb load asymmetry. Additionally, external loading from carrying a child may alter the degree of asymmetric loading that exists in the lower limbs. Therefore, the first purpose of this study was to investigate the effect of daily tasks on lower extremity load symmetry using metrics that have successfully identified load asymmetry in other populations. Load symmetry was found to differ between task, with the largest asymmetry occurring between limbs during the sit-to-stand task for the peak impact force (PIF = 9.08% symmetry) and during the stair descent task for the average loading rate (ALR = 15.43% symmetry). The increase in asymmetry during these tasks may be attributed to increased muscle activation and force production. The second purpose of this study was to investigate the effect of an external child load on lower extremity load asymmetry during a 14-meter level walking task. A significant increase was found between the no load and both child load conditions for PIF and ALR (p <0.001 for both metrics). No statistically significant differences in symmetry were found between carrying the child centrally in a carrier and carrying on one side of the body without a carrier. The lack of difference in asymmetry during child carrying conditions may indicate mothers naturally compensate for the external child load as both ALR and PIF values increased during these conditions, but asymmetry was not impacted. Our results indicate the need to continue to examine different carrying conditions in postpartum women to better understand risk factors for pain or injury and provide evidence-based recommendations for postpartum activity progression. / Master of Science / In 2021, over three and a half million women entered the postpartum period in the United States [1]. Despite their prevalence, postpartum health is a largely overlooked area and 25% of women experience low back or pelvic pain past the typical postpartum period of 8 weeks post delivery [3]. Research has found women may continue to experience this pain years after delivery and result from the lower limbs being loaded unequally. The extra weight from carrying a child may also impact the amount of unequal loading placed onto the lower limbs. The first purpose of this study was to investigate the effect of daily tasks on load symmetry in the lower limbs using measures that have successfully identified unequal load distribution in non-pregnant individuals. Load symmetry was found to differ between task, with the largest asymmetry occurring between limbs during the sit-to-stand task for the force applied to lower limbs during initial contact of the feet and during the stair descent task for the rate that force was applied to lower limbs. The second purpose of this study was to investigate the effect of an external child load on lower extremity load asymmetry during a 14-meter level walking task. A significant increase was found between the no load and both baby load conditions for force applied during initial contact of the feet and rate this force was applied. No difference was found between child carrying external loading condition when evaluating asymmetry. Our results indicate the need to continue to investigate the unique loading patterns of postpartum women to better understand the specific risk factors for pain or injury development within this population.

Section 1: Watershed-based Plan, Section 2: Pollutant Risk Ranking, Section 3: Watershed Management and Improvements, Appendix A: Soil Classification, Appendix B: Water Quality Data and Assessments, Appendix C: AGWA Tool, Appendix D: Suggested Readings

The highly fertile Amazonian Dark Earths (ADE) results from landscape transformations found in association with archaeological sites throughout Amazonia. In the Lower Tapajos region, ADEs are found in ancient Tapajó settlements dated to the Late Pre-Columbian period (AD 1000-1600). This research focuses on plant management associated with the regional formation of ADE. Three ADE sites are analysed for microbotanical remains. Phytolith and microcharcoal (< 125μm) from test pits and excavation profiles reveal diverse plant-use including food and non-food plants. Geochemical data indicated a variety of formations processes intra-site. The inter-site comparison indicated a gradiente of vegetation change related with the formation of ADEs. Aditionally, small changes folloed the adoption of cultigens together with ADE formation. These data suggest the practice of polyculture agroforestry in the investigated sites.

The whole universe is filled with plasma. There are different kinds of plasmas filling large volumes, separated by distinct boundaries. Many important energy conversion, particle acceleration and plasma transport processes occur at these boundaries, and therefore it is important to study the plasma processes there. It will for example help us to better understand the interaction and energy exchange between the Sun and the Earth. The lower hybrid drift waves (LHDW) are strong plasma waves that are often excited within boundaries, but their role in different plasma processes are still unclear. Many studies of the LHDW have been done, both in space and in laboratory. However, the LHDW are electron scale waves, and due to their small wavelength it has been difficult to study them in detail experimentally. For the first time we are able to make very detailed studies of the LHDW using observations by the Cluster spacecraft in the plasma surrounding Earth. By making cross spacecraft correlations of the electric field and examining existence conditions, we were able to determine the velocity of propagation and wavelength of the waves and thereby identify them as LHDW. We also calculate the electrostatic potential and find that it corresponds to about a third of the electron temperature. This indicate that they might be able to affect the electrons and thus take part in the processes within the boundary layer. By deriving a linear relation between the electrostatic potential, and the wave magnetic field, we compare them both and find that they correspond very well. We can use this to estimate the electrostatic potential in cases when cross spacecraft correlation is not possible.

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Nitrate pollution of ground and surface water can stem from the mismanagement and over-application of both inorganic and organic fertilizers. This results in the occurrence of non-point externalities, which infringe on the overall level of social welfare. Market based environmental policies, known as economic instruments, can be developed to curb the level of this non-point externality. Such policies directly affect the management decisions of agricultural producers, providing them with incentives to change their management practices. The overall objective of this study is to analyze an array of economic instruments which could feasibly curb water quality degradation resulting from the over-application and misuse of manure and inorganic fertilizers in agricultural production. The economic instruments are compared in terms of their relative effectiveness in decreasing nitrate water pollution and social damage. This thesis develops a three agent manure market model, wherein a vegetable producer and composter can purchase manure from a dairy producer or inorganic fertilizer from an exogenous fertilizer market. The production activities of each agent are modelled using real world production data. A non-linear programming technique is used. The imposition of a percentage manure tax was found to alter the vegetable producer’s derived demand for manure, and resulted in less manure being exchanged between the dairy and vegetable producers. The provisions of a percentage manure composting subsidy increased the quantity of manure demanded by the composter and decreased the amount of manure consumed by the vegetable and dairy producers. The imposition of an inorganic fertilizer tax increased the demands for manure fertilizer, as did the manure application limit. The effects on social damage are dependent on the leaching and surface run-off susceptibilities of each operation’s associated land base. The composting subsidy appeared to be the most efficient instrument for decreasing the overall level of social damage, when qualitatively analyzed. It induced decreases in the demand for manure by both the dairy and vegetable producers, while increasing the demand for manure of the composter. This results in an overall social benefit. There must be, however, financial justification for the implementation of such an instrument.

Medical social workers from health care institutions in the urban lower mainland of British Columbia were asked about their views, values and practice regarding passive and active euthanasia. This qualitative, exploratory study focused on the attitudes, values and structures that influence professional social work practice with clients requesting euthanasia. During the months of August to November, 1994, seventeen medical social workers, who were experienced in this area, were interviewed. An interview guide format was used that was previously tested in a pilot study of this project. Within the pre-selected categories; views, values and practice, responses were described and emerging themes were identified through content analysis. The study results confirm medical social workers are playing an active professional role with terminally-ill patients, families and staff when requests are made for euthanasia in the health care system. In this study population, in most cases, the social worker's views, whether for or against euthanasia, did not determine his/her practice with patients. Instead, it was the social worker's willingness to give up his/her control in the patient/professional relationship in an effort to support the patient's decision to die with dignity. This practice was based on the value of patient self-determination being paramount against all other interests. Self-determination was ranked as the most influential factor in determining practice by most of the participants. Responses revealed there was a lack of understanding by health care professionals at all levels regarding the process of separating personal values from the professional obligation to respect patient self-determination. Feminist medical ethics suggests that all health care professionals need to engage in self-evaluation to address any need they may have for power and control in the professional/patient relationship. Furthermore, medical social workers should recognize their own such needs, particularly when their personal views and values come into conflict with a patient's decision regarding euthanasia. This study not only presents the issues of power and control that social workers and other health care professsionals experience in the medical system, it also explores and describes the contributions social workers have made in their practice with patients who request the right to die with dignity.