Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2017-10-04T22:45:46Z No. of bitstreams: 1 RudolfoHummelGurgelVieira_DISSERT.pdf: 1108627 bytes, checksum: a120294a9853b95a77ea8c276df585b6 (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2017-10-14T00:19:17Z (GMT) No. of bitstreams: 1 RudolfoHummelGurgelVieira_DISSERT.pdf: 1108627 bytes, checksum: a120294a9853b95a77ea8c276df585b6 (MD5) / Made available in DSpace on 2017-10-14T00:19:17Z (GMT). No. of bitstreams: 1 RudolfoHummelGurgelVieira_DISSERT.pdf: 1108627 bytes, checksum: a120294a9853b95a77ea8c276df585b6 (MD5) Previous issue date: 2017-06-02 / Introdu??o: A hist?ria natural da Doen?a Pulmonar Obstrutiva Cr?nica est? associada a numerosas manifesta??es sist?micas e comorbidades que complicam sua evolu??o. Dessas, a disfun??o dos m?sculos esquel?ticos e respirat?rios destacam-se por acarretar um comprometimento na capacidade funcional. Objetivo: Avaliar e comparar a for?a muscular respirat?ria e perif?rica em pacientes com DPOC e indiv?duos saud?veis. Metodologia: Trata-se de um estudo transversal, anal?tico e observacional, no qual foram avaliados 18 indiv?duos, sendo nove com DPOC e nove saud?veis. Foram avaliados quanto ao desempenho neuromuscular do quadr?ceps femoral (avaliado por meio da dinamometria isocin?tica), for?a de preens?o manual (dinam?metro manual) e press?es respirat?rias m?ximas (manovacuometria). Os dados foram expressos por meio de m?dia e desvio padr?o, analisados no pacote estat?stico SPSS 20.0. Foi considerado um n?vel de signific?ncia de 5% e intervalo de confian?a de 95% para todas as medidas. Resultados: Os indiv?duos com DPOC apresentam desempenho neuromuscular de quadr?ceps femoral e press?es respirat?rias m?ximas inferiores aos sujeitos saud?veis, no entanto houve diferen?a estatisticamente significante apenas para pot?ncia muscular e PIm?x (p<0,05). J? a for?a de preens?o manual foi maior em indiv?duos com DPOC (p<0,05). Conclus?o: Os sujeitos com DPOC possuem altera??es neuromusculares em m?sculos perif?ricos e respirat?rios que possivelmente podem causar redu??o do desempenho funcional. / Introduction: The natural history of Chronic Obstructive Pulmonary Disease is associated with numerous systemic manifestations and comorbidities that complicate its evolution. Of these, dysfunction of the skeletal and respiratory muscles are characterized by a compromised functional capacity. Objective: To evaluate and compare respiratory and peripheral muscle strength in patients with COPD and healthy individuals. Methodology: This is a cross-sectional, analytical and observational study, in which 18 individuals were evaluated, nine of them with COPD and nine healthy. The femoral quadriceps neuromuscular performance (assessed by means of isokinetic dynamometry), hand grip strength (manual dynamometer) and maximum respiratory pressure (manovacuometry) were evaluated. The data were expressed by mean and standard deviation, analyzed in the statistical package SPSS 20.0. A significance level of 5% and a 95% confidence interval for all measures were considered. Results: Individuals with COPD had lower quadriceps femoral neuromuscular performance and lower respiratory pressures than healthy subjects; however, there was a statistically significant difference only for muscle power and MIP (p <0.05). Hand grip strength was higher in individuals with COPD (p <0.05). Conclusion: COPD subjects have neuromuscular changes in peripheral and respiratory muscles that may possibly cause reduced functional performance.