About fifty years ago, research began in the field of computational human phantoms primarily for radiation dose calculations. This field has grown exponentially due to the potential for solving complicated medical problems. Modeling electromagnetic, structural, thermal, and acoustic response of the human body to different internal and external stimuli has been limited by the availability of numerically efficient computational human models. This study describes the recent development of a computational full-body human phantom €“ Visible Human Project (VHP) €“ Female Model. This human phantom has been validated for certain frequencies in the ISM band and beyond. The anatomical accuracy of the phantom is established by comparing the CAD phantom with the original VHP image dataset. This thesis also applies the VHP €“ Female CAD Model (version 3.1) for investigating the effects of MRI radiation. The simulation environment ANSYS HFSS is used for studying the effects of RF birdcage coil on the human phantom. Finally, a non-ionizing technique for osteoporosis detection is investigated numerically.