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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

In Vitro Flow Visualization Study of the Interface between Outflow Graft of Ventricular Assist Device and Aorta.

Thatte, Suhas Madhusudan 01 January 2006 (has links)
Heart transplant is often considered the best treatment for prolonged left ventricular failure. However due to limited donor hearts and ineligibility of some patients to get a transplant, heart assist devices are considered a short/long term option to assist the failing ventricle. Numerous in vitro and animal trials are conducted to study the flow fields in artificial ventricles to avoid hemolysis and thrombosis but the effects of flow fields corresponding to the angle of LVAD insertion into the aorta are often neglected. This experiment uses 30, 60 and 90 degree glass models to signify different angles of the surgical end to side anastomosis. Particle Image Velocimetry is used to study the flow fields at the interface and determine optimum angle amongst the three to avoid blood trauma. Use of a 30 degree glass interface minimizes stagnation zone, recirculation patterns, flow reversal, high shear region and other flow irregularities which may lead to reduced hemolysis, thrombosis and blood trauma in a clinical setting.

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