Over the past decade, wireless sensor networks have gained more research attention for their potential applications in healthcare, defense, environmental monitoring, etc. Due to the strict energy limitation in the sensor node, techniques used for energy saving are necessary for this kind of network. MIMO technology is proven to be an effective method of increasing the channel capacity and supporting higher data rate under a fixed power budget and bit-error-rate requirement. So, wireless sensor networks and MIMO technology are combined and investigated in this thesis. The key contributions of this thesis are detailed below. Firstly, the extended total energy consumption equations for different transmission modes in cluster-based wireless sensor networks are derived. The transmitting energy consumption and the circuit energy consumption are taken into account in both intra-cluster and inter-cluster phases respectively. Secondly, a resource allocation framework is proposed for cluster-based cooperative MIMO on consideration of circuit energy. By introducing two adjusting parameters for the transmitting energy and the time slot allocation between intra-cluster and inter-cluster phases, this framework is designed to achieve the maximum data throughput of the whole system whilst maintaining the capacity and outage probability requirement in these two phases respectively. Thirdly, on comparison of various transmission modes in wireless sensor networks, a relatively energy-efficient mode switching framework is proposed for both single-hop and multi-hop transmissions. Based on the destination and the neighboring nodes’ path-loss, the source node can decide which transmission mode, SISO or cooperative MISO, single-hop or multi-hop, should be chosen. Conditions for each mode switching are investigated. The possible existing area of the cooperative nodes and the relaying nodes can be obtained from this framework.