Class of 2006 Abstract / Objectives: To describe the current response rate of pharmacists to mailed surveys and to identify the factors that influence pharmacist response rates. A number of hypotheses have been presented. Design: A systematic literature review. Methods: Included articles were evaluated for variables of interest using a data extraction form. Variables included length of survey, use of incentive, proximity, use of announcement, the anonymity of the survey, use of a reminder, and presence of return postage. Results: A total of 76 articles were identified of which 54 met inclusion criteria. The mean response rate for the survey was 45.8 percent. The effect on response rate was evaluated in regard to survey length, the inclusion of an incentive, and the geographical origination of the survey. The change in response rate for each single increase in the number of questions in a survey changed the response rate by 0.001 percent. Response rate for surveys without an incentive provided was 44.6 percent (SD = 0.168), while the response rate for those with an incentive was 50.7 percent (p > 0.277). Twenty seven surveys were deemed to seek responses from pharmacists in a close proximity to the organization sending out the survey (e.g., within the same state or region). Twenty-seven did not focus on a specific state or region. The mean response rates were 45.5 percent and 46.1 percent, respectively (p=0.882). There was no statistical significance in any of the other variables examined. Conclusions: This review of literature addressing pharmacist response rate to mailed surveys revealed that pharmacists’ response to surveys is not significantly affected by survey length, inclusion of an incentive, or survey origin.