Las expediciones a Salinas Grandes constituían actividades complejas que requerían planificación y una importante movilización de recursos y personas. Los itinerarios seguidos por las carretas de la sal y los lugares en los que se montaban los campamentos mientras duraba su recolección constituyeron escenarios de variadas interacciones entre hispano-criollos e indígenas. Pero no sólo se trataba de obtener el producto sino que, al mismo tiempo, se procuraba entrar en contacto con los caciques locales para establecer todo tipo de intercambios y negociaciones, llevar a cabo actividades de inteligencia, y rescatar cautivos. Estos intereses, compartidos por los grupos indígenas, daban lugar a jornadas de intensa actividad registradas en diarios, relaciones y cartas. A través de su análisis pudimos conocer que estas travesías estuvieron caracterizadas por un número significativo de aspectos que las convirtieron en travesías vulnerables pero que, a pesar de ello, los conflictos no escalaron a niveles mayores de violencia gracias a una serie de factores que estudiaremos a lo largo de este trabajo, entre los que cobraron una importancia fundamental los cautivos indígenas e hispanocriollos, como asimismo los intérpretes que desempeñaron roles diversos. / The expeditions to Salinas Grandes were complex activities that required planning and a significant mobilization of resources and people. The itineraries followed by the salt carts and the places where the camps were set up while their collection lasted constituted scenes of varied interactions between hispanic-creole and native people. But it was not only about obtaining the product, but at the same time, it was trying to get in touch with the local chiefs to establish all kinds of exchanges and negotiations, carry out intelligence activities, and rescue captives. These interests, shared by native groups, gave rise to days of intense activity recorded in newspapers, relationships and letters. Through their analysis we were able to know that these expeditions were characterized by a significant number of aspects that made them vulnerable crossings, but that despite this, individual conflicts did not escalate to higher levels of violence thanks to a series of factors that we will study throughout this work, among which native and hispanic-creole captives took on fundamental importance, as well as interpreters who played diverse roles.