During an era when the Seminoles were little regarded in Florida, despite mass Indian reform nationwide, Minnie Moore-Willson of Kissimmee and Ivy Stranahan of Fort Lauderdale attempted to bring reform to the state. Living amongst members of the tribe, both women used their familiarity with Seminole life and practices, as well as their political and social connections, to enact change for the tribe. This was done, respectively, through the creation of reservations and attempting to increase educational and vocational opportunities for tribe members. This thesis examines the lives and activism of Minnie Moore-Willson and Ivy Stranahan over the first two decades of the twentieth century and details their attempts to reform federal and state policies towards Seminoles in Florida. It illustrates the relationships of the women with each other, the Seminoles, and political power brokers in early twentieth century Florida, and attempts to determine their motivations. In doing so, the thesis argues that, though often ignored in the historiography of Seminoles in Florida, these women served as key figures in enacting Seminole-related reforms during the era. Examining Moore-Willson and Stranahan's lives and works affords a greater understanding of how non-Seminole women conceptualized and carried out Florida reform efforts and provides a new perspective for evaluating the early stages of Florida Seminole reform and comparable efforts in other areas of the United States.