Sponges (Porifera) are the most primitive multicellular animals that are highly diverse and complex associated with other organisms, microbes especially. Recently, sponges have received a lot of attention as they are a rich source of nature products with antiviral, antitumor, and antimicrobial activities. Sponges play such important roles in so many marine habitats but little is known about their diversity, biology and ecology as compared with most other animal groups. Moreover, due to limited information provided based on morphology, other method of classification is need. Mitochondrial DNA sequence may fulfill such purpose. The complete nucleotide sequence (19444 bp) of the mt genome of the Cinachyrella australiensis (Demospongiae: Spirophorida) was determined. The genome contains the two rRNA, 24 tRNA and 14 protein-coding genes. We found that poriferan mtDNAs resemble those of other animals in their compact organization, and a well-conserved animal-like gene order. However, this molecule has several unique features: the ATP 9 gene is the first found to be present in the mt genome of multicellular animals, the cytochrome c oxidase subunit I (COI) gene include a group I intron, and encode bacteria-like tRNA. The results represent that the evolution of metazoan mtDNA has been a multistep process to the reduction of tRNA and the introduction of multiple changes of the translation code.

Thesis (Ph.D.)--University of Delaware, 2009. / Principal faculty advisor: Benjamin D. Fleury-Steiner, Dept. of Sociology & Criminal Justice. Includes bibliographical references.

Thesis (Honors)--College of William and Mary, 2009. / Includes bibliographical references (leaves 51-54). Also available via the World Wide Web.

Thesis (Ph. D.)--York University, 1999. Graduate Programme in Biology. / Typescript. Includes bibliographical references (leaves 135-144). Also available on the Internet. MODE OF ACCESS via web browser by entering the following URL: http://wwwlib.umi.com/cr/yorku/fullcit?pNQ39261.

Thesis (M. Sc.)--York University, 2001. Graduate Programme in Kinesiology and Health Science. / Typescript. Includes bibliographical references (leaves 84-88). Also available on the Internet. MODE OF ACCESS via web browser by entering the following URL: http://wwwlib.umi.com/cr/yorku/fullcit?pMQ66403.

The mitochondnal genome was screened for genetic variation associated with production traits in White Leghorns. Analysis was done on an unselected randomly mated population of White Leghorn chickens. An AsnI restriction fragment length polymorphism (RFLP) was detected in the control region of the mitochondrial genome, a region responsible for transcription and replication. The RFLP segregated at a frequency of 0.76 for the AsnI (+) allele (presence of an AsnI restriction site). The AsnI RFLP was in linkage disequilibrium with a previously detected MspI RFLP in the NADH sub-unit IV of the mitochondrial genome for the same population of White Leghorns. Genotypes were denoted as follows: The first sign represented individuals that were positive (+) or negative (-) for the MspI restriction site, where as the second denoted whether individuals were positive or negative for the AsnI restriction site. Comparison of the three genotypic classes (+,+), (-,+) and (-,-) revealed that (-,-) individuals had a significantly higher body weight (5.5%) than individuals of the other genotypes. Dot blot analysis revealed no difference in the mitochondrial DNA copy number in peripheral blood cells between AsnI(-) or AsnI(+) individuals.

Thesis (M. Sc.)--University of Canterbury, 2005. / Typescript (photocopy). Includes bibliographical references (leaves [96-108]). Also available via the World Wide Web.

Thesis (M.S.)--Ohio University, June, 2008. / Title from PDF t.p. Includes bibliographical references.

Thesis (Ph. D.)--University of Canterbury, 2008. / Typescript (photocopy). Includes bibliographical references. Also available via the World Wide Web.

Thesis (Ph. D.)--University of California, San Diego, 1998. / Vita. Includes bibliographical references.