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Systematics of the genus Candida; implications for understanding clinical presentation, mixed infection and antifungal treatment and the influence on strain maintenance and replacement during oral candidiasis in HIV-infected individualsFraser, Michelle (Michelle Lousie) January 2002 (has links) (PDF)
"8th July 2002." Includes bibliographical references (leaves 276-308) Examines the systematics (taxonomy, phylogeny, and epiemiology) of the genus Candida using a combination of traditional and contemporary methodologies. Assesses these methods to determine their diagnostic potential to unequivocally identify and characterise species and strains of this medically and dentally important yeast genus.
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Systematics of the genus Candida; implications for understanding clinical presentation, mixed infection and antifungal treatment and the influence on strain maintenance and replacement during oral candidiasis in HIV-infected individuals / by Michelle Fraser.Fraser, Michelle Louise January 2002 (has links)
"8th July 2002." / Includes bibliographical references (leaves 276-308) / vi, 308, [57] leaves : charts ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Examines the systematics (taxonomy, phylogeny, and epiemiology) of the genus Candida using a combination of traditional and contemporary methodologies. Assesses these methods to determine their diagnostic potential to unequivocally identify and characterise species and strains of this medically and dentally important yeast genus. / Thesis (Ph.D.)--University of Adelaide, Dept. of Dentistry, 2002
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Epiteloidcellig granulomatos - etiologi och remitteringshandhavande vid oral histopatologisk diagnosBokander, Linda, Nilsson, Klara January 2013 (has links)
Epiteloidcellig granulomatos (ECG) är en patologanatomisk diagnos (PAD) av en inflammationstyp som kan ses i orala vävnadsbiopsier. Inflammationsbilden visar infiltrat av inflammationsceller och epiteloidcelliga granulom med eller utan jätteceller, därtill kan ödematös vävnad och fibros presenteras. Makroskopiskt ses en symtombild med t ex läpp- och ansiktssvullnad, munvinkelragader och gingivala hyperplasier. Klinisk ställs exklusionsdiagnosen orofacial granulomatos (OFG). Etiologin är multifaktoriell och kan ses vid exempelvis Crohns sjukdom (CS) och sarkoidos. På Avdelning för Oral Patologi, Malmö Tandvårdshögskola, sker PAD av biopsier som vid ECG diagnoskodas med 995, vilket tilldelats 152 remissfall. Metoden utgörs av en retrospektiv uppföljning av dessa remisser med syfte att undersöka etiologin, utfört remitteringshandhavande, samt för att få en uppfattning om den orala biopsin bidragit till eventuell systemisk sjukdomsdiagnos och huruvida återkoppling mellan remissinstanserna förekommit. Vidare undersöktes om ett eventuellt samarbete mellan tandläkare och läkare praktiserats.Antalet deltagande vårdgivare i studien visar på ett intresse för ECG och dess etiologi. Misstänkt etiologi var i de flesta fall CS vilket stämde överens med ställd diagnos. Remitteringshandhavandet visade i vissa fall på bristande återkoppling mellan inkluderade vårdinstanser och vårdgivare samt avsaknad av förutbestämda remitteringsvägar. Andra remissfall visade väl fungerande samarbete mellan vårdyrken och instanser samt att den orala biopsin i vissa fall bidragit till ställd systemisk sjukdomsdiagnos. Författarna önskar att studien i förlängningen ska kunna bidra till väl fungerande kommunikation mellan berörda vårdgivare med förhoppning om snabbare handhavande, säkrare patienthantering med tidigare ställd diagnos och minskat lidande för patienterna. / Epithelioid cell granulomatosis (ECG) is a diagnosis of anatomical pathology (PAD) and a type of inflammation seen in oral biopsies. ECG presents with histological features such as epithelioid cell granuloma with or without presence of multinucleated giant cells, inflammatory cells and occasionally oedematous fibrotic changes. Clinical symptoms presents as e.g. enlargement of lips, facial swelling, angular cheilitis and gingival hyperplasia. Orofacial granulomatosis (OFG) is the clinical diagnosis given PAD ECG with a multifactorial aetiology e.g. Crohn’s disease (CS) and sarcoidosis. The Department of Oral Pathology, Faculty of Odontology, Malmö University, determine PAD of oral biopsies that when given ECG are marked with the code of diagnosis 995, given 152 referrals. This retrospective follow-up of referrals with PAD ECG aims to investigate represented aetiology, management of referrals and to get a notion of whether the oral biopsy has contributed to systemic diagnosis, if there has been any feedback between included instances and collaboration between dentists and physicians. Number of included participants could be interpreted as an interest in ECG, which most frequently showed to be CS, agreeing with later confirmed diagnosis. The management in some cases of referral lacked feedback between health professionals as well as absence of predetermined ways of referral. Others showed cooperation and that the oral biopsy had contributed to diagnosis of systemic disease. The authors wish that this study will contribute to a well functional communication between health professionals, anticipating a more efficient and secure management of patients, improvement of early diagnosis and decreased patient discomfort.
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