Bibliography: p. 184-215. / xvii, 215, [122] p., [21] leaves of plates : ill. ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / Aims to clone the gene for [alpha]-L-iduronidase, to enable molecular genetic diagnosis of mutations causing Mucopolysaccharidosis type I for more accurate disease prognosis, and make possible new therapy protocols such as enzyme replacement therapy and gene replacement therapy. / Thesis (Ph.D.)--University of Adelaide, Dept. of Pathology, 1993