This dissertation aims to provide models which will help companies make sustainable logistics management and transportation decisions. These models are extensions of the economic lot sizing model with the availability of multiple replenishment modes. The objective of the models is to minimize total replenishment costs and emissions. The study provides applications of these models on contemporary supply chain problems. Initially, the impact of carbon regulatory mechanisms on the replenishment decisions are analyzed for a biomass supply chain under fixed charge replenishment costs. Then, models are extended to consider multiple-setups replenishment costs for age dependent perishable products. For a cost minimization objective, solution algorithms are proposed to solve cases where one, two or multiple replenishment modes are available. Finally, using a bi-objective model, tradeoffs in costs and emissions are analyzed in a perishable product supply chain.