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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
61

Expression of adiponectin receptors by vascular smooth muscle cells

Stevenson, Meredith J. Fay, William P. January 2009 (has links)
The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from PDF of title page (University of Missouri--Columbia, viewed on January 5, 2010). Thesis advisor: William P. Fay. Includes bibliographical references
62

Ionic conductances involved in the electrical activity of the canine gastrointestinal tract /

Flynn, Elaine Rose Maria January 1999 (has links)
Thesis (Ph. D.)--University of Nevada, Reno, 1999. / Includes bibliographical references. Online version available on the World Wide Web.
63

Effects of endothelin-1 on coronary smooth muscle after chronic diabetes, atherogenic diet, and therapy /

Lee, Dexter L., January 2000 (has links)
Thesis (Ph. D.)--University of Missouri--Columbia, 2000. / "May 2000." Typescript. Vita. Includes bibliographical references (leaves 152-178). Also available on the Internet.
64

Regulation of coronary smooth muscle intracellular Ca²⁺ levels in porcine models of hyperlipidemia, diabetic dyslipidemia, and exercise training /

Witczak, Carol A. January 2003 (has links)
Thesis (Ph. D.)--University of Missouri--Columbia, 2003. / "May 2003." Typescript. Vita. Includes bibliographical references (leaves 121-137).
65

Role of the G protein-coupled receptor kinase 2 in mediating transforming growth factor beta and G protein-coupled receptor signaling and crosstalk mechanisms

Mancini, Johanna. January 2007 (has links)
Transforming growth factor beta (TGFbeta) and Angiotensin II (AngII) signaling occurs through two distinct receptor superfamilies, the serine/threonine kinase and G protein-coupled receptors (GPCRs). Through diametric actions, TGFbeta and AngII regulate various biological responses, including cell proliferation and migration. Previously, we identified the G protein-coupled receptor kinase 2 (GRK2), which acts through a negative feedback loop mechanism to terminate Smad signaling. To investigate the impact of TGFbeta-induced GRK2 expression on GPCR signaling, we examined its effect on AngII signaling in vascular smooth muscle cells (VSMCs). We show that activation of the TGFbeta signaling cascade results in increased GRK2 expression levels, consequently inhibiting AngII-induced ERK phosphorylation and antagonizing AngII-induced VSMC proliferation and migration. The inhibitory effect of TGFbeta on AngII signaling occurs at the MEK-ERK interface and is abrogated when an anti-sense oligonucleotide directed against GRK2 is used. Thus, we conclude that TGFbeta signaling antagonizes AngII-induced VSMC proliferation and migration through the inhibition of ERK phosphorylation. GRK2 is a key factor in mediating this crosstalk.
66

The role of incretin peptides and ghrelin in upper gut motility and metabolic control /

Edholm, Therese, January 2006 (has links)
Diss. (sammanfattning) Stockholm : Karolinska institutet, 2006. / Härtill 4 uppsatser.
67

Lysophosphatidic acid : physiological effects and structure-activity relationships /

Nilsson, Ulrika K. January 2002 (has links)
Diss. (sammanfattning) Linköping : Univ., 2002. / Härtill 4 uppsatser.
68

Development of intimal hyperplasia in transplant arteriosclerosis /

Religa, Piotr, January 2003 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst., 2003. / Härtill 4 uppsatser.
69

Perlecan in vascular disease /

Tran, Phan Kiet, January 2005 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst., 2005. / Härtill 5 uppsatser.
70

Studies of the novel PDGFs, focusing on PDGF-D /

Folestad, Erika Bergsten, January 2006 (has links)
Diss. (sammanfattning) Stockholm : Karolinska institutet, 2006. / Härtill 4 uppsatser.

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