by Carrie Au-Yeang. / Thesis (M.Phil.)--Chinese University of Hong Kong, 1997. / Includes bibliographical references (leaves 45-54). / Abstract also in Chinese. / Chapter I. --- Abstract --- p.iii / Chapter II. --- Acknowledgements --- p.iv / Chapter III. --- Table of Contents --- p.v / Chapter IV. --- List of Abbreviations --- p.vii / Chapter V. --- List of Figures --- p.viii / Chapter VI. --- List of Tables --- p.ix / Chapter VII. --- Introduction --- p.1 / Chapter VIII. --- Literature Review --- p.3 / Chapter A. --- Mycobacterium tuberculosis Infections - clinical importance --- p.3 / Chapter B. --- Treatment of M. tuberculosis Infections - the past & present --- p.3 / Chapter C. --- Laboratory Supports for Treatment of Tuberculosis --- p.5 / Chapter D. --- The Postantibiotic Effects (PAE) --- p.6 / Chapter E. --- PAE of Antituberculosis Drugs Against Mycobacteria --- p.15 / Chapter F. --- Radiometric Measurement of growth --- p.16 / Chapter IX. --- Materials and Methods --- p.17 / Chapter A. --- Bacterial Strains and Their Maintenance --- p.17 / Chapter B. --- Antimicrobial Agents --- p.17 / Chapter C. --- Antimicrobial Susceptibility Testing --- p.18 / Chapter D. --- Assessment of PAE and KI In Vitro --- p.20 / Chapter E. --- Assessment of PAE and KI Ex Vivo --- p.22 / Chapter F. --- Determination of Drug Uptake --- p.25 / Chapter X. --- Results --- p.29 / Chapter A. --- In Vitro Susceptibility Testing of the M. tuberculosis Strains --- p.29 / Chapter B. --- PAE In Vitro - the Classical Viable Count Method --- p.29 / Chapter C. --- PAE Measured by the Bactec Method --- p.30 / Chapter D. --- PAE In Vitro - the Bactec Method --- p.30 / Chapter E. --- Postantibiotic Effects Ex Vivo by the Bactec Method --- p.31 / Chapter F. --- Bactericidal Activities In Vitro and Ex Vivo --- p.32 / Chapter XI. --- Discussion --- p.34 / Chapter A. --- Selection of M. tuberculosis isolates and Drug Susceptibility --- p.34 / Chapter B. --- PAE and KI In Vitro & Ex Vivo - the study methods --- p.34 / Chapter C. --- PAE In Vitro & Ex Vivo - single drug --- p.36 / Chapter D. --- PAE Ex Vivo - drug combinations --- p.38 / Chapter E. --- KI In vitro & Ex vivo --- p.39 / Chapter F. --- PAE and Clinical Therapeutic Regimens --- p.41 / Chapter G. --- Conclusion & Future Studies --- p.44 / Chapter XII. --- Literature Cited --- p.45 / Chapter XIII. --- Figures --- p.55 / Chapter IVX --- Tables --- p.68