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Dissertation submitted in partial compliance with the requirements for the Master’s Degree in Technology: Homoeopathy, Durban University of Technology, 2013. / The addition of a large number of new remedies to the homoeopathic materia medica has made it challenging to select the correct remedy for a patient. Locating individual remedies within groups makes it easier to understand, remember and apply the information from the remedies. The aim of this research study was to evaluate common themes and symptomatology of homoeopathic remedies belonging to the synthetic recreational drug isolate group, as represented in the known homoeopathic materia medica and repertory. Most remedies derived from synthetic recreational drug isolate sources have not been well documented or comprehensively proven in homoeopathy, so are not well represented in repertory programs. Therefore, in addition, remedies in this study were selected according to the homoeopathic significance of each remedy, the availability of actual provings and representation in materia medica, the existence of a synthetic derivative of the drug, and if the drug was commonly used. The selected remedies were then subjected to a manual rubric extraction process in which common rubrics were extracted. The common rubrics were analyzed to determine common sensations within the group. The extracted sensations were then defined using a dictionary and synonyms were determined using a thesaurus. Each sensation was subjected to a literature search to test its validity. Second and third order analyses were performed based on the results. The most common sensations found as a result of this process were: dryness, itching, fear, anger, restlessness, anxiety, indifference, heaviness, heat, acute and weakness. The active and passive reactions and compensations of the synthetic recreational drug isolate group were also analyzed. The active reactions included anger, rage, acute, violence, impatience and irritation. Passive reactions were heaviness, numbness, dullness, faintness, weakness and coldness. The compensatory reaction included sensations of ecstasy, elation and euphoria or tranquillity. Each remedy was classified into specific miasms based on Sankaran’s miasmatic model (Sankaran, 1997). Each remedy was categorized as a particular miasm if the literature showed a clear predominance of the themes associated with that miasm. Many of the remedies had features of the AIDS, Cancer, Sycotic and Tubercular miasms. Pathological tendencies of the synthetic recreational drug isolate group involved the throat, eyes, stomach, nervous system, male genitalia and sleep patterns. Clinically, the remedies can be used in cases of mental disorders such as psychosis and schizophrenia, chronic fatigue, visual and sleeping disorders, anorexia nervosa and neurological disorders such as chorea, tremors and formication. The results of this study appear to confirm the application of the group analysis methodology as outlined by Sankaran (2002). The results also add depth to the existing literature on synthetic recreational drug isolate remedies. / M