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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
1

Application of the in vivo metabolic blocking technique to the study of the metabolism of cancer

Busch, Harris. January 1952 (has links)
Thesis (Ph. D.)--University of Wisconsin, 1952. / Typescript (carbon copy). Charts laid in. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references.
2

Experimental studies on the susceptibility of certain mouse tumours to lowered temperature in vivo compared with the susceptibility of normal mouse tissue ...

Eltorm, Helge. January 1946 (has links)
Thesis--Copenhagen. / Summaries in English and Danish. Translated from the Danish by Anna La Cour. Bibliography: p. 145-149.
3

The histogenesis of experimental bladder cancer.

Tiltman, Andrew John 20 April 2017 (has links)
No description available.
4

Retinoids in experimental neuroblastoma therapy /

Ponthan, Frida, January 2003 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst., 2003. / Härtill 5 uppsatser.
5

Die tierische Zelle in Zellkultur /

Schindler, Richard January 1965 (has links)
Zugl.: Habil'schrift Bern.
6

Multiple genetic factors contribute to the differential genetic susceptibility of Copenhagen and Fischer 344 rats to mammary carcinogenesis /

Ren, Xuefeng. January 2007 (has links)
Thesis (Ph. D.)--University of Washington, 2007. / Vita. Includes bibliographical references (leaves 132-182).
7

Recombinant antibodies and tumor targeting /

Sheikholvaezin, Ali, January 2006 (has links)
Diss. (sammanfattning) Umeå : Univ., 2006. / Härtill 4 uppsatser.
8

Prostaglandins and angiogenesis in experimental cancer /

Axelsson, Hans, January 2010 (has links)
Diss. (sammanfattning) Göteborg : Göteborgs universitet, 2010. / Härtill 4 uppsatser.
9

NF-kB in epidermal signal transduction and tumor development /

Hogerlinden, Max van, January 2002 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst., 2002. / Härtill 4 uppsatser.
10

Antitumor activities of extracts and fractions from Wedelia trilobata.

January 2002 (has links)
Yip Nga-lam. / Thesis (M.Phil.)--Chinese University of Hong Kong, 2002. / Includes bibliographical references (leaves 151-164). / Abstracts in English and Chinese. / Abstract --- p.i / Abstract (Chinese Version) --- p.iii / Acknowledgements --- p.v / Table of Contents --- p.vi / List of Tables --- p.xi / List of Figures --- p.xii / List of Abbreviations --- p.xv / Chapter Chapter 1 --- Introduction --- p.1 / Chapter Chapter 2 --- Literature Review --- p.6 / Chapter 2.1 --- Medicinal Plants and Herbs --- p.6 / Chapter 2.1.1 --- Antitumor activities --- p.8 / Chapter 2.1.1.1 --- Successful examples - Camptothecin --- p.8 / Chapter 2.1.1.2 --- Successful examples - Taxol --- p.13 / Chapter 2.2 --- Compositae and its Traditional Functions --- p.16 / Chapter 2.3 --- Antitumor Activity of Compositae --- p.19 / Chapter 2.3.1 --- Emilia sonchifolia --- p.19 / Chapter 2.3.2 --- Silymarin --- p.20 / Chapter 2.4 --- Wedelia Species --- p.22 / Chapter 2.4.1 --- Hepatoprotective effect --- p.22 / Chapter 2.4.2 --- Hypoglycemic effect --- p.23 / Chapter 2.4.3 --- Antimicrobial activity --- p.23 / Chapter 2.4.4 --- Antinociceptive activity --- p.24 / Chapter 2.4.5 --- Antifeedant and antifungal activities --- p.24 / Chapter 2.4.6 --- Trypanosomicidal effect --- p.25 / Chapter 2.4.7 --- Chemical constituents --- p.25 / Chapter 2.5 --- Sesquiterpene lactone --- p.27 / Chapter 2.6 --- Cell Cycle Control and Apoptosis --- p.30 / Chapter 2.6.1 --- Cell cycle and its control in cancer therapy --- p.30 / Chapter 2.6.2 --- Apoptosis --- p.36 / Chapter 2.7 --- Four Selected Compositae Species Used in the Study --- p.42 / Chapter 2.7.1 --- Dendranthema indicum (野菊花) --- p.42 / Chapter 2.7.2 --- Dendranthema morifolium (菊花) --- p.43 / Chapter 2.7.3 --- Taraxacum mongolicum --- p.44 / Chapter 2.7.4 --- Wedelia trilobata (三裂葉蟛蜞菊) --- p.45 / Chapter Chapter 3 --- Materials and Methods / Chapter 3.1 --- Extraction --- p.47 / Chapter 3.1.1 --- Water extraction --- p.47 / Chapter 3.1.2 --- NaOH extraction --- p.48 / Chapter 3.1.3 --- Ethanol precipitation --- p.50 / Chapter 3.1.4 --- Bioactivity guided fractionation --- p.50 / Chapter 3.1.4.1 --- Macroporous resin column (D101) --- p.50 / Chapter 3.1.4.2 --- Silica gel 60 column --- p.51 / Chapter 3.1.5 --- High Performance Liquid Chromatography (HPLC) analysis --- p.53 / Chapter 3.2 --- Characterization --- p.54 / Chapter 3.2.1 --- Chemical tests --- p.54 / Chapter 3.2.1.1 --- Alkaloids --- p.54 / Chapter 3.2.1.1.1 --- Mayer reagent --- p.54 / Chapter 3.2.1.1.2 --- Dragendorff reagent --- p.54 / Chapter 3.2.1.1.3 --- Wagner reagent --- p.55 / Chapter 3.2.1.2 --- Lactones and coumarins --- p.55 / Chapter 3.2.1.2.1 --- Ferric hydroxamine acid test --- p.55 / Chapter 3.2.1.2.2 --- Emersen reagent --- p.56 / Chapter 3.2.1.3 --- Flavonoids --- p.56 / Chapter 3.2.1.3.1 --- Shinoda test --- p.56 / Chapter 3.2.1.3.2 --- Aluminum chloride reagent --- p.56 / Chapter 3.2.1.4 --- Sterols --- p.57 / Chapter 2.2.1.4.1 --- Liebermann-Buchard test --- p.57 / Chapter 3.2.1.4.2 --- Salkowski reaction --- p.57 / Chapter 3.2.1.5 --- Saponins --- p.57 / Chapter 3.2.1.6 --- Carbohydrates --- p.58 / Chapter 3.2.1.6.1 --- Molisch reagent --- p.58 / Chapter 3.2.1.6.2 --- Aniline acetate reaction --- p.58 / Chapter 3.2.1.7 --- Terpenoids --- p.58 / Chapter 3.2.1.7.1 --- Vanillin reagent --- p.58 / Chapter 3.2.1.7.2 --- Carr-price reagent --- p.59 / Chapter 3.2.1.8 --- Anthraquinone --- p.59 / Chapter 3.2.1.8.1 --- Borntrager reaction --- p.59 / Chapter 3.2.1.8.2 --- Magnesium acetate reagent --- p.59 / Chapter 3.2.2 --- X-ray crystallography --- p.60 / Chapter 3.3 --- In vitro Assay --- p.61 / Chapter 3.3.1 --- Cell lines --- p.61 / Chapter 3.3.2 --- Maintenance of cell lines --- p.61 / Chapter 3.3.3 --- In vitro antitumor assay --- p.62 / Chapter 3.3.3.1 --- Trypan blue exclusion method --- p.63 / Chapter 3.3.3.2 --- MTT assay method --- p.65 / Chapter 3.3.3.3 --- Determination of IC50 --- p.66 / Chapter 3.3.4 --- Cytotoxicity assay on normal cell lines --- p.67 / Chapter 3.4 --- In vivo Assay --- p.68 / Chapter 3.4.1 --- Animals --- p.68 / Chapter 3.4.2 --- Maintenance of Sarcoma 180 cell line --- p.68 / Chapter 3.4.3 --- Tumor inoculation --- p.69 / Chapter 3.4.4 --- Preparation of samples --- p.69 / Chapter 3.4.5 --- In vivo antitumor assay --- p.70 / Chapter 3.4.5.1 --- Antitumor effect of WT4-4 on Sarcoma 180 solid tumor --- p.70 / Chapter 3.4.5.2 --- Effect of 5% DMSO in sterile PBS --- p.70 / Chapter 3.4.6 --- Body weight change --- p.71 / Chapter 3.5 --- DNA Agarose Gel Electrophoresis --- p.73 / Chapter 3.6 --- Statistical Analysis --- p.74 / Chapter Chapter 4 --- Results / Chapter 4.1 --- Extraction and characterization of Wedelia trilobata (WT) --- p.76 / Chapter 4.1.1 --- Percentage of yield in extraction and fractionation of WT --- p.76 / Chapter 4.1.2 --- HPLC chromatograms of WT fractions and the purified component (crystal) --- p.77 / Chapter 4.1.3 --- Phytochemical groups of WT4-4 --- p.78 / Chapter 4.1.4 --- Results on X-ray crystallography of the isolated crystal from WT4-4 A --- p.78 / Chapter 4.2 --- In vitro Antitumor Assay --- p.95 / Chapter 4.2.1 --- "Effects ofDIl, DM1, TM1 and WT1 on suspension cancer cell line" --- p.95 / Chapter 4.2.2 --- Effects of WT fractions and the purified component (crystal) on suspension cell lines --- p.95 / Chapter 4.2.3 --- Effects of WT fractions on adhesive cancer cell lines --- p.98 / Chapter 4.2.4 --- Effects of WT4-4 on normal cell lines --- p.98 / Chapter 4.3 --- In vivo Antitumor Effect of WT4-4 --- p.126 / Chapter 4.4 --- Results of DNA Agarose Gel Electrophoresis --- p.130 / Chapter Chapter 5 --- Discussion / Chapter 5.1 --- Characterization of Antitumor Fraction and Compound of Wedelia trilobata (WT) --- p.132 / Chapter 5.2 --- Antitumor Effects of WT Fractions and Purified Component (Crystal) --- p.137 / Chapter 5.2.1 --- In vitro assay --- p.137 / Chapter 5.2.2 --- DNA agarose gel electrophoresis --- p.143 / Chapter 5.2.3 --- In vivo assay --- p.144 / Chapter 5.3 --- Further Study --- p.146 / Chapter Chapter 6 --- Conclusion --- p.148 / References --- p.151

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