Diss. (sammanfattning) Stockholm : Karol. inst. / Härtill 7 uppsatser.

Diss. (sammanfattning) Uppsala : Uppsala universitet, 2006. / Härtill 4 uppsatser.

Diss. (sammanfattning) Stockholm : Karol. inst. / Härtill 5 uppsatser.

Es tracta d'un estudi epidemiològic de les neoplàsies limfoides a Tarragona. Es donen dades d'incidència, mortalitat, supervivència i prevalença en base poblacional de les 3.258 neoplàsies limfoides del Registre de Càncer de Tarragona durant el període 1980-2004 ( 354 limfomes de Hodgkin, 1605 limfomes no-Hodgkin (LNH), 676 mielomes múltiples, 188 leucèmies limfàtiques agudes i 435 leucèmies limfàtiques cròniques). S'ha estudiat la tendència temporal de la incidència i la seva projecció a 2010 i 2015 per a cada grup de malalties. Els LNH s'han classificat histològicament d'acord amb la classificació de l'OMS de les neoplàsies hematològiques, i s'han establert comparacions internacionals. Les principals conclusions han estat que les neoplàsies limfoides a Tarragona mostren un patró epidemiològic occidentalitzat, amb una progressiva millora en la seva supervivència relativa, i que existeix, almenys parcialment, una relació temporal entre la epidèmia de la SIDA i la dels LNH. / This is an epidemiological study of lymphoid neoplasms in Tarragona, a southern region of Catalonia with a population over 800.000. It gives details of incidence, mortality, survival and prevalence in a population basis of 3,258 lymphoid malignancies recorded in the Tarragona Cancer Registry during the period 1980 to 2004 (354 Hodgkin's lymphoma, 1605 non-Hodgkin's lymphoma (NHL), 676 multiple myeloma, 188 acute lymphocytic leukemia and 435 chronic lymphocytic leukemia). We have studied the incidence time trend and its projection to 2010 and 2015 for each disease group. The NHL were classified histologically according to WHO classification of hematologic malignancies, and their relative frequency were compared internationally. The main conclusions were that the lymphoid malignancies in Tarragona show a westernized epidemiological pattern, with a progressive improvement in their relative survival and that there is at least partially, a temporal relationship between the AIDS and the NHL epidemics.

by Suk-yee Fung. / Thesis (M.Phil.)--Chinese University of Hong Kong, 1995. / Includes bibliographical references (leaves 95-107). / Abstract --- p.i / Acknowledgement --- p.ii / Table of Contents --- p.iii / List of Tables --- p.v / List of Figures --- p.vii / List of Appendices --- p.viii / Chapter Chapter I - --- Introduction --- p.1 / Introduction --- p.1 / Epidemiology of Breast Cancer --- p.2 / The Aetiology of Breast Cancer --- p.4 / Prognosis --- p.4 / Effects of Breast Cancer --- p.5 / Management of Breast Cancer --- p.6 / Prevention and Early Detection of Breast Cancer --- p.8 / Theoretical Framework --- p.18 / Chapter Chapter II - --- Method --- p.39 / Research Design --- p.39 / Sample --- p.40 / Measures --- p.41 / Procedure --- p.48 / Data Analysis --- p.49 / Chapter Chapter III - --- Results --- p.50 / Chapter 1 --- Sample Characteristics --- p.50 / Chapter 1.1 --- Demographic profile --- p.50 / Chapter 1.2 --- Medical history and health practices --- p.52 / Chapter 1.3 --- Health status and health values --- p.53 / Chapter 1.4 --- Knowledge of breast cancer --- p.54 / Chapter 1.5 --- Attitudes toward breast cancer --- p.55 / Chapter 2 --- Breast Self-Examination Practices --- p.57 / Chapter 3 --- Social Influence on Breast Self-Examination Practices --- p.60 / Chapter 4 --- Health Belief Model Measures --- p.61 / Chapter 5 --- Comparison of Practicers and Non-practicers --- p.62 / Chapter 6 --- Predictors of breast self-examination practices --- p.67 / Chapter 6.1 --- Practicers vs Non-practicers --- p.67 / Chapter 6.2 --- Frequency of breast self-examination --- p.70 / Chapter 6.3 --- Breast self-examination intention --- p.75 / Chapter Chapter IV - --- Discussion & Conclusions --- p.77 / Discussion --- p.77 / Conclusions --- p.93 / References --- p.95 / Appendices --- p.108

Wang Ya-ping. / Thesis (M.Phil.)--Chinese University of Hong Kong, 1994. / Includes bibliographical references (leaves 111-120). / CONTENT / ACKNOWLEDGMENT / ABSTRACT / Chapter Chapter 1. --- Introduction / Chapter Chapter 2. --- Review of relevant literature / Chapter 2.1 --- Mammary structure and embryology / Chapter 2.2 --- Pathology of breast cancer / Chapter 2.3 --- Risk factors in breast cancer / Chapter 2.4 --- Prognostic factors in breast cancer / Chapter 2.5 --- Treatment of breast cancer / Chapter 2.6 --- Breast cancer research by flow cytometry / Chapter 2.7 --- c-erbB-2 oncogene research in breast cancer / Chapter 2.8 --- Tables and figures of chapter2 / Chapter Chapter 3. --- Materials and methods / Chapter 3.1 --- Flow cytometry assay of breast cancer tissue / Chapter 3.1.1 --- Sample collection / Chapter 3.1.2 --- Sample preparation for flow cytometric assay / Chapter 3.1.3 --- DNA content assay by flow cytometry / Chapter 3.1.4 --- Solutions for flow cytometric analysis / Chapter 3.2 --- c-erbB-2 and EGF receptor protein detection by immunohistochemical methods / Chapter 3.2.1 --- Preparation of sections / Chapter 3.2.2 --- Methods of staining / Chapter 3.2.3 --- Methods of analysis / Chapter 3.2.4 --- Confirmation of expression of c-erbB-2 protein by immunoblotting method / Chapter 3.2.5 --- Solutions for immunohistochemical and immunoblotting methods / Chapter 3.3 --- Clinical data from 346 breast cancer patients and method of analysis / Chapter 3.4 --- Tables and figures of chapter3 / Chapter Chapter 4. --- Results / Chapter 4.1 --- Results of flow cytometric analysis / Chapter 4.1.1 --- Tumour characteristics of 94 breast cancer patients / Chapter 4.1.2 --- Survival analysis by results of flow cytometry / Chapter 4.2 --- Results of immunohistochemical assay of c-erbB-2 and EGFr / Chapter 4.2.1 --- C-erbB-2 and EGFr expression in breast cancer / Chapter 4.2.2 --- The distribution of c-erbB-2 and EGFr expression in breast cancer / Chapter 4.2.3 --- Analysis of clinical outcome by c-erbB-2 and EGFr expression / Chapter 4.3 --- Clinical data of 346 patients with breast cancer / Chapter 4.3.1 --- Patients' characteristics / Chapter 4.3.2 --- Analysis of clinical data and outcome / Chapter 4.3.3 --- Analysis of clinical outcome according to histopathological characteristics of breast tumour / Chapter 4.3.4 --- Types of operation and clinical outcome / Chapter 4.3.5 --- Postoperative adjuvant therapy and clinical outcome / Chapter 4.3.6 --- Results from statistical analysis by Cox-regression / Chapter 4.4 --- Tables figures of chapter4 / Chapter Chapter 5. --- Discussion and conclusion / Chapter 5.1 --- Flow cytometric analysis of paraffin-embedded breast cancer tissue / Chapter 5.1.1 --- Evaluation of DNA flow cytometric results / Chapter 5.1.2 --- Correlation between tumor DNA aneuploidy or cell subpopulation and clinical outcome / Chapter 5.1.3 --- Correlation between S-phase fraction of breast tumour and clinical outcome / Chapter 5.1.4 --- Observation of high proportion of DNA hypoaneuploidy in this study / Chapter 5.2 --- c-erbB-2 oncogene overexpression in breast cancer / Chapter 5.2.1 --- c-erbB-2 oncoprotein expression in other studies / Chapter 5.2.2 --- Correlation between c-erbB-2 oncoprotein expression status and breast cancer pathogenesis / Chapter 5.3 --- Evaluation of EGFr expression in breast cancer / Chapter 5.4 --- Analysis of clinical data / Chapter 5.4.1 --- Clinical characteristics of patients with breast cancer / Chapter 5.4.2 --- Clinical characteristics of breast cancer and clinical outcome / Chapter 5.4.3 --- Clinical outcome by types of postoperative treatment / Chapter 5.5 --- Prognostic factors / Chapter 5.5.1 --- Our observations in comparison to other studies / Chapter 5.5.2 --- Prognostic factors for clinical application / Chapter 5.6 --- Tables and figures of chapter5 / References:

Introdução. O câncer de boca em 1998 foi a décima-primeira localização mais comum das neoplasias malignas, exceto pele, no sexo masculino, em São Paulo, com 1,6% dos casos. Dados do Registro de Câncer de São Paulo mostram que a incidência não diminuiu em anos recentes. A região é de alta incidência para esse tipo de câncer, em comparação às demais regiões brasileiras e mesmo em termos mundiais. Julgou-se de interesse de Saúde Pública verificar a incidência do câncer de boca no Município de São Paulo, segundo sexo e idade, em anos selecionados. Objetivos. Descrever os coeficientes de incidência de câncer de boca no Município de São Paulo em 1969, 1973, 1978 e 1998, segundo sexo, idade e localização topográfica do tumor, comparando-os; calcular a probabilidade de incidência de câncer de boca em intervalos selecionados de idade segundo sexo e localização topográfica do tumor. Métodos. Partindo-se de dados secundários (Registro de Câncer de SP), obtiveram-se as taxas de incidência e calcularam-se as taxas de incidência acumulada segundo sexo e localização topográfica em intervalos de 5 anos. Os riscos acumulados para até as idades de 20,30,...,70 anos, em porcentagem, foram calculados e apresentados em gráficos seguindo o modelo de Zdeb modificado por Souza; para análise estatística foram construídos intervalos de confiança para os riscos, segundo sexo e localização topográfica, comparando-se as suas magnitudes. Resultados e comentários. Observou-se redução de riscos de câncer de lábio, entre 1969 e 1998, em ambos os sexos. Aumentos de riscos em orofaringe e cavidade bucal, no sexo feminino, poderiam estar relacionados a incremento do tabagismo entre mulheres no período. / Introduction. In 1998, oral cancer was the eleventh most frequent site of all malignant neoplasms in São Paulo, in males, comprising 1.6% of the global incidence (except for the cancer of skin). According to the São Paulo Cancer Registry this incidence has not decreased in recent years. Furthermore, this type of cancer is highly frequent in this city in comparison with other Brazilian regions as well as in the world. The incidence of oral cancer according to sex and age regarding selected years was considered to be of interest to Public Health. Objectives. To describe and to compare incidence rates of oral cancer in São Paulo City in 1969, 1973, 1978 and 1998, according to sex, age and site of the tumor; to calculate the probability of the incidence of oral cancer over selected age-intervals, according to sex and localization of tumour. Methods. Population based incidence data was obtained from São Paulo Cancer Registry, allowing calculation of cumulative incidence rates according to sex and topographic site along 5-year intervals. Cumulative risks until ages of 20,30,...,70 years, in percent, were then calculated and presented graphically following Zdeb model, modified by Souza. Confidence intervals were build up for statistical analysis of risks according to sex and site of the tumor, allowing comparisons of their magnitudes. Results and comments. Lip cancer risks have decreased, in both sexes, between 1969 and 1998. Increase of risks was observed in oropharynx and oral cavity, in females. This result could be related to an increasing prevalence of tobacco use in females, in São Paulo, as have been reported by several surveys carried out in this city.

Introdução. O câncer de boca em 1998 foi a décima-primeira localização mais comum das neoplasias malignas, exceto pele, no sexo masculino, em São Paulo, com 1,6% dos casos. Dados do Registro de Câncer de São Paulo mostram que a incidência não diminuiu em anos recentes. A região é de alta incidência para esse tipo de câncer, em comparação às demais regiões brasileiras e mesmo em termos mundiais. Julgou-se de interesse de Saúde Pública verificar a incidência do câncer de boca no Município de São Paulo, segundo sexo e idade, em anos selecionados. Objetivos. Descrever os coeficientes de incidência de câncer de boca no Município de São Paulo em 1969, 1973, 1978 e 1998, segundo sexo, idade e localização topográfica do tumor, comparando-os; calcular a probabilidade de incidência de câncer de boca em intervalos selecionados de idade segundo sexo e localização topográfica do tumor. Métodos. Partindo-se de dados secundários (Registro de Câncer de SP), obtiveram-se as taxas de incidência e calcularam-se as taxas de incidência acumulada segundo sexo e localização topográfica em intervalos de 5 anos. Os riscos acumulados para até as idades de 20,30,...,70 anos, em porcentagem, foram calculados e apresentados em gráficos seguindo o modelo de Zdeb modificado por Souza; para análise estatística foram construídos intervalos de confiança para os riscos, segundo sexo e localização topográfica, comparando-se as suas magnitudes. Resultados e comentários. Observou-se redução de riscos de câncer de lábio, entre 1969 e 1998, em ambos os sexos. Aumentos de riscos em orofaringe e cavidade bucal, no sexo feminino, poderiam estar relacionados a incremento do tabagismo entre mulheres no período. / Introduction. In 1998, oral cancer was the eleventh most frequent site of all malignant neoplasms in São Paulo, in males, comprising 1.6% of the global incidence (except for the cancer of skin). According to the São Paulo Cancer Registry this incidence has not decreased in recent years. Furthermore, this type of cancer is highly frequent in this city in comparison with other Brazilian regions as well as in the world. The incidence of oral cancer according to sex and age regarding selected years was considered to be of interest to Public Health. Objectives. To describe and to compare incidence rates of oral cancer in São Paulo City in 1969, 1973, 1978 and 1998, according to sex, age and site of the tumor; to calculate the probability of the incidence of oral cancer over selected age-intervals, according to sex and localization of tumour. Methods. Population based incidence data was obtained from São Paulo Cancer Registry, allowing calculation of cumulative incidence rates according to sex and topographic site along 5-year intervals. Cumulative risks until ages of 20,30,...,70 years, in percent, were then calculated and presented graphically following Zdeb model, modified by Souza. Confidence intervals were build up for statistical analysis of risks according to sex and site of the tumor, allowing comparisons of their magnitudes. Results and comments. Lip cancer risks have decreased, in both sexes, between 1969 and 1998. Increase of risks was observed in oropharynx and oral cavity, in females. This result could be related to an increasing prevalence of tobacco use in females, in São Paulo, as have been reported by several surveys carried out in this city.

Lin, Hualiang. / Thesis (Ph.D.)--Chinese University of Hong Kong, 2011. / Includes bibliographical references (leaves 140-177). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Abstract also in Chinese.

Chan Kay Sheung Paul. / "December 2002." / Thesis (M.D.)--Chinese University of Hong Kong, 2002. / Includes bibliographical references (p. 225-254). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Electronic reproduction. Ann Arbor, MI : ProQuest Information and Learning Company, [200-] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Mode of access: World Wide Web.