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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
21

Immune recognition molecules in synaptic plasticity and regeneration of spinal motoneurons

Thams, Sebastian, January 2009 (has links)
Diss. (sammanfattning) Stockholm : Karolinska institutet, 2009.
22

Effect of maternal care on maternal responsiveness and astrocyte plasticity in the medial amygdala and medial preoptic nucleus in the rat

McAllister, Kelli. January 2007 (has links)
Estrogen acts on maternal circuitry to establish maternal behaviour in otherwise non-maternal rats. The precise mechanisms by which estrogen primes maternal circuitry are unknown; however, the medial preoptic area (MPOA) stimulates maternal behaviour whilst the medial amygdala (MeA) inhibits it. This thesis aimed to address the link between estrogen sensitivity, astroglia and maternal behaviour. Maternal care influences maternal behaviour of female offspring. One mechanism underlying this influence is differential estrogen sensitivity within the MPOA. Estrogen receptor alpha (ERalpha) expression was examined in offspring of High and Low licking/grooming (LG) dams within the MPOA. Enhanced expression ERalpha was limited to the medial preoptic nucleus in offspring of High LG dams and the anteroventral periventricular nucleus in Low LG dams. Adult nulliparous offspring of High and Low LG dams were assessed for maternal responsiveness using the pup sensitization paradigm. Offspring of Highs showed maternal behaviour significantly earlier than offspring of Lows. Brains of pup-exposed and pup-naive High and Low offspring were analyzed for astroglial markers glial fibrillary acidic protein (GFAP) and glutamine synthetase. Pup-naive animals showed more GFAP positive cells within the posteroventral MeA, with no differences within the MPOA and no effect of maternal care. Glutamine synthetase, a glial-derived enzyme necessary for glutamate production, showed greater expression within the MeA of High LG pup-naive animals; with no maternal care differences observed in pup-experienced animals. Thus, long-lasting changes within maternal circuitry established in early life are reflected in regionally specific enhanced estrogen sensitivity and latency to display maternal behaviour, but the effects are less clear with respect to astroglia.
23

The long-term teratogenic effect of prenatal alcohol exposure on the somatosensory and motor cortex of rats

Chappell, Tyson, January 2007 (has links) (PDF)
Thesis (Ph.D.)--University of Tennessee Health Science Center, 2007. / Title from title page screen (viewed on February 29, 2008). Research advisor: Robert S. Waters, Ph.D. Document formatted into pages (xix, 179 p. : ill.). Vita. Abstract. Includes bibliographical references (p. 152-178).
24

On regulation of hippocampal neurogenesis : roles of ethanol intake, physical activity and environment /

Åberg, Elin, January 2007 (has links)
Diss. (sammanfattning) Stockholm : Karolinska institutet, 2007. / Härtill 6 uppsatser.
25

The influence of amyloid-beta, a major pathological marker in Alzheimer's disease, on molecular cognitive processes of APP+PS1 transgenic mice

Dickey, Chad Anthony. January 2004 (has links)
Thesis (Ph. D.)--University of South Florida, 2004. / Includes vita. Includes bibliographical references.
26

Chemical and stimulus-induced NMDA-dependent synaptic plasticity in hippocampus and the possible involved mechanisms /

Li, Rui, January 2006 (has links)
Diss. (sammanfattning) Göteborg : Göteborgs universitet, 2006. / Härtill 4 uppsatser.
27

The N-cadherin prodomain regulation of synpase formation in vivo and developmental expression pattern in the zebrafish central nervous system /

Sadeghi, Nazlie. January 1900 (has links)
Thesis (Ph.D.). / Written for the Dept. of Neurology and Neurosurgery. Title from title page of PDF (viewed 2008/07/24). Includes bibliographical references.
28

Circadian oscillation of MAPK activity and cAMP in the hippocampus : implications for memory persistence /

Mahan, Kristin Lynn. January 2008 (has links)
Thesis (Ph. D.)--University of Washington, 2008. / Vita. Includes bibliographical references (leaves 110-127).
29

Changes in short-term facilitation are opposite at Schaffer collateral and Temporoammonic CA1 synapses in the developing rat hippocampus

Speed, Haley E. January 2008 (has links) (PDF)
Thesis (Ph. D.)--University of Alabama at Birmingham, 2008. / Title from first page of PDF file (viewed Sept. 22, 2008). Includes bibliographical references.
30

The role of CREB-dependent gene expression in neuronal plasticity and memory formation /

Impey, Soren. January 1998 (has links)
Thesis (Ph. D.)--University of Washington, 1998. / Vita. Includes bibliographical references (leaves [143]-175).

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