Self-control has been defined as the ability to override or alter an automatic response. Past research has suggested that those who are higher in the personality trait neuroticism display poorer self-control. Based on theory suggesting that self-control is a limited resource, the present study attempts to explain the relationship between neuroticism and self-control. Understanding that neuroticism is characterized by emotional instability, it follows that individuals high in neuroticism must exert more self-control in managing their negative moods, thus leaving them depleted for future acts of self-control. Participants (n = 84) completed measures of trait self-control, engaged in an emotional regulation task, and then completed measures of state self-control, affect, and rumination. Results revealed no significant effect of emotional regulation on state self-control, nor a significant effect of neuroticism on state self-control. The implications of these findings are discussed.