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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
31

Neurobiological basis of the nicotine withdrawal reaction : an experimental analysis /

Hildebrand, Bengt E., January 1900 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst. / Härtill 6 uppsatser.
32

Examining the behavioral and molecular aspects of adolescent nicotine dependence implications for vulnerability to drug abuse /

Kota, Dena Heath, January 1900 (has links)
Thesis (Ph.D.)--Virginia Commonwealth University, 2008. / Title from title-page of electronic thesis. Prepared for: Dept. of Pharmacology and Toxicology. Bibliography: leaves 163 - 177.
33

Comparison of three methods for measuring smoking behavior /

Blank, Melissa D., January 2007 (has links)
Thesis (Ph. D.)--Virginia Commonwealth University, 2007. / Prepared for: Dept. of Psychology. Bibliography: leaves 106-118. Also available online.
34

A test of elaborated intrusion theory manipulating vividness of imagery interventions on cigarette craving /

Murray, Shanna L. January 2008 (has links)
Thesis (Ph.D.)--Bowling Green State University, 2008. / Document formatted into pages; contains vii, 75 p. Includes bibliographical references.
35

Regulation of the endogenous opioid system by acute nicotine and nicotine withdrawal

McCarthy, Michael J., January 2004 (has links)
Thesis (Ph. D.)--Ohio State University, 2004. / Title from first page of PDF file. Document formatted into pages; contains xiii, 172 p.; also includes graphics (some col.). Includes bibliographical references (p. 131-172 ). Available online via OhioLINK's ETD Center
36

Studies on the ulcerogenic mechanisms of nicotine and its withdrawal on stress-induced gastric ulceration in the rat /

Wong, Donna. January 1996 (has links)
Thesis (Ph. D.)--University of Hong Kong, 1997. / Includes bibliographical references (leaf 181-226).
37

Examining the behavioral and molecular aspects of adolescent nicotine dependence : implications for vulnerability to drug abuse /

Kota, Dena Heath, January 2008 (has links)
Thesis (Ph.D.)--Virginia Commonwealth University, 2008. / Prepared for: Dept. of Pharmacology and Toxicology. Bibliography: leaves 163 - 177. Also available online via the Internet.
38

The involvement of matrix metalloproteinases in nicotine conditioned place preference in adolescent female rats

Natarajan, Reka. January 2009 (has links) (PDF)
Thesis (Ph. D.)--Washington State University, December 2009. / Title from PDF title page (viewed on Sept. 9, 2009). "Program in Neuroscience." Includes bibliographical references.
39

The significance of withdrawal in a multidisciplinary profile of tobacco dependence

Hayward, Robert C. January 2003 (has links)
No description available.
40

EPIGENETIC TRANSMISSION OF NICOTINIC EFFECTS WITHIN THE NEONATAL QUINPIROLE RODENT MODEL OF SCHIZOPHRENIA

Gill, Wesley, Hernandez, Liza J, Whicker, Wyatt S, Burgess, Kate C, Kaestner, Charlotte L, Brown, Russell W 05 April 2018 (has links)
Schizophrenia is a neurological disorder found in approximately 1% of the population. It is estimated that as many as 88% of individuals diagnosed which schizophrenia smoke tobacco, a rate which is greatly increased compared to the general population. While increased use of nicotine-containing products such as cigarettes may be detrimental to the long-term health of individuals with schizophrenia, it has been hypothesized that nicotine use is a form of self-medication for these individuals who suffer from serious neurological and psychological symptoms such as hallucinations, delusions, anhedonia, and cognitive impairments. Understanding the biomolecular mechanisms which result in a higher propensity for smoking may lead to an overall better understanding of the disease and new treatment options. This study investigated the effects of nicotine in an epigenetic transmission model of schizophrenia. Rats were treated neonatally with the dopamine D2 agonist quinpirole or saline from P1 to P21 and then raised into adulthood. This paradigm has been previously shown to produce rats with symptoms similar to schizophrenia, including an enhanced response to nicotine. These neonatally treated rats were then bred to produce pups which were not neonatally treated to investigate whether schizophrenia-like symptoms would be transmitted to the untreated offspring of the quinpirole treated parents in the context of nicotine administration, similar to that of their parents. To examine the effects of nicotine, the rats that were the offspring of animals that were neonatally treated quinpirole were behaviorally tested on either a behavioral sensitization or conditioned place preference (CPP) paradigm, and animals received either nicotine or saline. Following behavioral testing, brain tissue was collected, and an ELISA for brain-derived neurotrophic factor (BDNF) was performed. Results revealed that these offspring demonstrated a heightened behavioral response to nicotine as well as increased expression of BDNF following nicotine administration if at least one parent rat was neonatally treated with quinpirole. This indicates that there may be epigenetic information passed from parents neonatally treated with quinpirole to the offspring.

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