This thesis surveys a variety of songs and arias for high soprano which feature the nightingale; examines the musical elements that symbolize, refer to, or imitate the nightingale; and compares these musical elements with transcriptions of the nightingale's song. The first chapter reviews the symbolic development of the nightingale and its role in poetry and literature. The interior chapters address a selection of musical compositions that feature the nightingale and its song. The final chapter establishes a relationship between the sound of the actual sound of the nightingale and the musical gestures created by composers to imitate the nightingale.