Cette etude pilote de six mois examinait si l'autogestion (AG) intensive par un agent secreteur d'insuline avait pour consequence une glycemie amelioree en comparaison avec une gestion standard (GS) chez les individus atteints de diabete de type 2. Des patients ont ete randomises soit a l'AG avec du repaglinide (n=8), ou du glyburide (n=6) ou a la GS (n=5). Des analyses biochimiques, alimentaires, comportementales, et d'activite physique ont ete effectuees. Les deux groupes de l'AG ont recu un enseignement d'autogestion en fonction du taux de glucose sanguin et une evaluation nutritionnelle qualitative. Le groupe AG (n=11) a suivi la cedule 65% du temps et a fait des ajustements 29% du temps. Une relation inverse significative a ete trouvee entre le changement de l'Alc et le pourcentage de temps d'ajustements accomplis correctement (r=0.64, p=0.035). La difference de masse corporelle entre l'AG et la GS n'etait pas significative, tout comme la masse corporelle moyenne a six mois. Une recherche plus approfondie avec un echantillon de plus grande taille serait necessaire afin d'explorer les avantages potentiels de la gestion du diabete via l'autogestion de medicaments oraux.

The objective of this study was to determine if teaching the new sugar guidelines, which now permit up to 10% of energy from added sugars, would modify dietary habits, metabolic control and perceived quality of life in free-living subjects with type 2 diabetes. In an eight month randomized controlled trial, 48 subjects with type 2 diabetes were taught, by a trained dietitian, either a conventional diabetic meal plan: conventional group (C) or one in which they could integrate the new sugar guidelines: sugar group (S). Patients were seen at the clinic every 2 months (total of 5 visits) by the dietitian and the endocrinologist. During the pre-randomization period (0 to 4 months) all subjects were taught the conventional diabetic diet and advised to avoid concentrated sugars. Randomization to the C or the S group took place at the 4 month visit (4 to 8 month period = post-randomization). The S group were taught how to use and integrate the Canadian Diabetes Association's new sugar choices (e.g. added sugar: honey, regular jam, white sugar, etc) into their daily diabetic meal plan. (Abstract shortened by UMI.)

It is estimated that approximately 80% of all persons with DM2 are obese, and the prevalence of diabetes increases With increasing age and body weight. Intensive control resulting in near-normal glycemia in obese DM2 holds great potential for reducing morbidity and mortality, but is associated with weight gain. In turn, modest weight loss improves glycemia considerably. Current weight loss programs, with decreasing frequency of interventions over time, result in a weight loss pattern of a U-shaped curve indicating an inability in maintaining the lower weight. We hypothesized that increasing vs decreasing frequency of treatment visits over time would result in better weight loss and metabolic control. Forty-eight DM2 subjects (28 F, 20 M; wt = 98 +/- 3 kg; BMI = 35 +/- 2 kg/m2; DM duration = 11 +/- 8 yrs) were stratified according to weight and level of glycated hemoglobin (HbA1c), and randomized to one of two protocols: decreasing frequency (DF) of visits, seen weekly (for 2 mos), bimonthly (for 3 mos) and monthly (for 3 mos) and increasing frequency (IF) of visits seen in the reverse order. Visits included 18 lifestyle, behaviour modification, group sessions and 5 individual evaluations at 0, 2, 4, 8 and 12 months. (Abstract shortened by UMI.)

No description available.

Thesis (Ph. D.)--Ohio State University, 2005. / Title from first page of PDF file. Document formatted into pages; contains xvii, 172 p.; also includes graphics Includes bibliographical references (p. 127-138). Available online via OhioLINK's ETD Center

Thesis (Ph.D.)--Kent State University, 2009. / Title from PDF t.p. (viewed April 16, 2010). Advisor: Margaret Doheny. Keywords: diabetes; self-management; type 2; qualitative. Includes bibliographical references (p. 160-172).

Thesis (M.A.)--West Virginia University, 2002. / Title from document title page. Document formatted into pages; contains ix, 91 p. : ill. Includes abstract. Includes bibliographical references (p. 46-51).

Thesis (Ph. D.)--University of Texas at Austin, 1998. / Vita. Includes bibliographical references (leaves 195-225). Available also in a digital version from Dissertation Abstracts.

Thesis (D.Clin.Psych.) - University of Queensland, 2004? / Includes bibliography.

Thesis (Ph.D.)--York University, 2008. Graduate Programme in Biology. / Typescript. Includes bibliographical references. Also available on the Internet. MODE OF ACCESS via web browser by entering the following URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:NR51727