In response to a NCAA ruling, North Texas State University (NTSU) launched a comprehensive drug testing, drug education and counseling program for its athletes effective August 1, 1986. This study assessed and compared NTSU student-athlete and student alcohol and drug use. In addition, attitudes toward a variety of sports-related drug topics, including mandatory athletic drug testing, were assessed and compared. The study revealed significant differences between student-athletes and students in drug use of the following: steroids, marijuana, cocaine, psychedelics, and amphetamines. Both groups favored mandatory drug testing of athletes.