With the advances in technology, the change of the healthcare environment, and the need for users, the use of computerized support systems or expert systems are able to cut down costs for unnecessary procedures, achieve higher levels of efficiency and productivity. Applied to the nursing department, it may provide good quality of care, decrease the time that nurses duplicate patient history, reduce nurses¡¦ burden and enhance the abilities to solve problems. The topic of this research mainly focused on the nursing department in the pediatric ward. I propose a framework for nursing knowledge management by using subjective data, objective data, assessment, and care plan (SOAP), which is used by the nursing staffs as a way of decision-making processes. The method is to collect subjective and objective data, read relevant clinical practice guidelines, make clinical judgments about patients¡¦ actual or potential problems and provide applicable nursing plans and interventions. The staffs review and make final decision to accept or reject these judgments, nursing plans and related interventions. If the staffs reject any judgment, nursing plan and intervention, the system should have inquiry-signs to ask physician and nursing staff. Then the staffs correct the inappropriateness. These clear and easy-to-follow processes help student nurses or beginning nurses cultivate their abilities to care and hope it can provide as a guide to nursing teaching and clinical patient care.