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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
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Showing 41 to 50 of 246 (0.01 seconds)| 41 |
Oligonucleotide-based lunimescent detection platform utilizing iridium (III) complexesLeung, Ka Ho 27 May 2015 (has links)
Luminescent transition metal complexes have arisen as viable alternatives to organic dyes for sensory applications due to their notable advantages. This thesis aimed to synthesize different kinds of Ir(III) complexes, explore their interactions with DNAs and investigate their application for the construction of label-free oligonucleotide-based sensing platforms. A series of Ir(III) complexes incorporating a variety of C^N and N^N donor ligands were synthesized and were shown to exhibit G-quadruplex-selective binding properties via emission titration, UV/vis titration, fluorescence resonance energy transfer melting and G-quadruplex fluorescent intercalator displacement experiments. These G-quadruplex-selective Ir(III) complexes were utilized as signal transducers to monitor the conformational changes of oligonucleotides in label-free oligonucleotide-based luminescent detection platforms for metal ion (Sr2+), small molecules (GSH and ATP), protein (human neutrophil elastase) and enzyme activities (polymerase, hepatitis C virus NS3 helicase).
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Synthesis, characterizations and applications of C2'-modified oligonucleotide analoguesPeng, Chang Geng. January 2007 (has links)
No description available.
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Synthesis physicochemical and biological studies on oligonucleotides containing D-arabinoseNoronha, Anne Marietta January 1999 (has links)
Note:
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Development of a novel methodology for the synthesis of oligonucleotide-peptide conjugates /Zaramella, Simone, January 2004 (has links)
Diss. (sammanfattning) Stockholm : Karol. inst., 2004. / Härtill 5 uppsatser.
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The synthesis of novel nucleoside analogues from nitroimidazolesGardner, S. J. January 1997 (has links)
No description available.
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MD simulations of bio-nano-system: controllable translocation and selective separation of single-stranded DNAs through a polarized CNT membrane謝迎洪, Xie, Yinghong. January 2007 (has links)
published_or_final_version / abstract / Mechanical Engineering / Doctoral / Doctor of Philosophy
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Reduction of huntingtin aggregation and transcript levels by utilization of guanine rich oligonucleotidesSkogen, Michael John. January 2007 (has links)
Thesis (M.S.)--University of Delaware, 2007. / Principal faculty advisor: Eric B. Kmiec, Dept. of Biological Sciences. Includes bibliographical references.
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Synthesis and oligomerization of Delta, 4-diamino-2-oxo-1(2H)-pyrimidinehexanoic acidHuang, Sung-ben 29 May 1990 (has links)
Graduation date: 1991
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Sorption studies of oligonucleotide DNA on montmorillonite clay : development of an improved assay protocol /Robson, Michael H. January 2009 (has links)
Thesis (M.S.)--Texas State University--San Marcos, 2009. / Vita. Reproduction permission applies to print copy: Blanket permission granted per author to reproduce. Includes bibliographical references (leaves 68-70).
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MicroRNA targeting with oligonucleotide analoguesTorres, Adrian Gabriel January 2012 (has links)
No description available.
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