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Projektivní interview u onkologicky nemocných dětí / Using Projective Interview with oncology deseased childrenKlasová, Karolína January 2015 (has links)
The thesis focuses on a social development of 10-12 years old oncologically ill children, more specifically on a social cognition and relations to objects. Projective interview test evaluated with a SCORS scale has been chosen as a main scientific tool. Theoretical part describes a relationship between an oncological disease and a psychosocial development. It also focuses on an early-adolescence as described in a developmental psychology, brings an explanation of a Projective interview and Westen's interpretative system - Social cognition and object relations scale SCORS. The second part of the thesis consists of a research which verifies the hypothesis that possible differences in the test results of healthy and oncologically ill children could be found. There have not been found any significant differences in a social development of oncologicaly ill children and a control group of healthy children on a quantitative level of statistical analysis. The results of the research can not be situated on a pathological scale and can be thus considered in a norm. Qualitative analysis has discovered differences in a perception of a family, school environment, friends and emotions. Keywords: Oncological diseases at children, psycho-oncology, Projective inteview, SCORS, social deficit and somatically ill persons
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Postoje rodičů a učitelů při vzdělávání žáka s chronickým onemocněním na 1. stupni běžné základní školy / Attitudes of parents and teachers in the education of a pupil with a chronic disease at the 1 st stage of a regular primary schoolVopatová, Kristina January 2021 (has links)
The diploma thesis deals with the attitude of parents and teachers of pupils with chronic diseases in the attenuation of compulsory school attendance at the 1st stage of ordinary primary school. The objective of the work is to identify the problems that parents and teachers of chronically ill students encounter during the educational process. From this basis, the purpose is also to find the basis for the best possible cooperation between parents and teachers. The theoretical idea is represented by individual chronic diseases, namely asthma, cystic fibrosis, pediatric oncological diseases, type 1 diabetes mellitus and epilepsy. In addition, the legislative framework for the education of pupils with these diseases, the methodology of working with pupils with chronic diseases and a search of domestic and foreign research conducted on a similar topic are addressed. The methodological part is devoted to qualitative research, the main goal of which is to find out the attitudes of teachers and parents to the educational process of pupils suffering from the above diseases. Using a questionnaire survey and a semi-structured interview, it is ascertained what are the attitudes of parents and teachers towards the education of pupils with the above-mentioned types of chronic diseases in ordinary primary school....
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Цитотоксическое действие синтезированных циклоплатинированных комплексов на культивируемые клетки глиобластомы человека : магистерская диссертация / Cytotoxic effect of synthesized cycloplatinated complexes on cultured human glioblastoma cellsКокшарова, Я. Б., Koksharova, Y. B. January 2022 (has links)
Проведено исследование цитотоксического действия синтезированных препаратов платины на нормальные клетки человека и различные линии опухолевых клеток. Выполнена оценка фрагментации ДНК методом электрофореза. Исследована целостность цитоплазматической мембраны клеток, подверженных действию препаратов платины. Выявлено наиболее перспективное соединение платины как возможный субстрат для разработки фармацевтических препаратов для лечения онкологических заболеваний. / Within the framework of this work, reviews of the literature on tumor cells and methods of combating malignant neoplasms, including those using platinum preparations, are collected. A study was made of the cytotoxic effect of the synthesized platinum preparations on normal human cells and various tumor cell lines. DNA fragmentation was studied by electrophoresis. A study was made of the integrity of the cytoplasmic membrane of cells exposed to platinum preparations. The most promising platinum compound has been identified as a possible substrate for the development of pharmaceutical preparations for the treatment of oncological diseases.
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