Population estimation in inter-censual years has many important applications. In this research, high-resolution pan-sharpened IKONOS image, LiDAR data, and parcel data are used to estimate small-area population in the eastern part of the city of Denton, Texas. Residential buildings are extracted through object-based classification techniques supported by shape indices and spectral signatures. Three population indicators -building count, building volume and building area at block level are derived using spatial joining and zonal statistics in GIS. Linear regression and geographically weighted regression (GWR) models generated using the three variables and the census data are used to estimate population at the census block level. The maximum total estimation accuracy that can be attained by the models is 94.21%. Accuracy assessments suggest that the GWR models outperformed linear regression models due to their better handling of spatial heterogeneity. Models generated from building volume and area gave better results. The models have lower accuracy in both densely populated census blocks and sparsely populated census blocks, which could be partly attributed to the lower accuracy of the LiDAR data used.