Structural health monitoring (SHM) is an emerging field in civil engineering in recent years. The main objectives of the SHM are to identify structural integrity issues at early stage and improve the structural safety through measuring and analyzing structural behaviors. Sensing systems for SHM can be used to identify applied vehicle loads for bridge structures. Bridge weigh-in-motion (BWIM) is one type of such vehicle load identification. As a tool to monitor the vehicle weight moving on the bridges, BWIM uses the structural responses induced by moving vehicle on the bridge to back-calculate vehicle information. In this thesis, optimized BWIM systems using multimetric measurements will be investigated. In Chapter 1, the concept and background of BWIM systems will be introduced. The objective of this research will be also demonstrated in this chapter. Chapter 2 is the literature review section. In Chapter 3, the finite element bridge model adopted for this study will be described. In this section, the moving-load time history analysis, sectional properties for bridge members, and other structural parameters of bridge model will be introduced. The methodology of BWIM systems used in this study will be demonstrated in Chapter 4. In Chapter 5, optimized sensor locations for BWIM using normal and shear strain measurements and acceleration measurement will be discussed for the case without measurement noise. In Chapter 6, sensor location optimization for the case considering measurement noises will be investigated. A new acceleration-based BWIM method is proposed in this section. Non-drift displacement reconstruction technique using acceleration measurement and FIR filtering is applied for BWIM. Finally, Chapter 7 is the conclusion part of this thesis.