This report explores the use of origami techniques in the space, medical and military fields. This new design method will modify the design process and reduce costs. The origami design method will also improve the device’s performance and quality of the device. The most important and complex procedures are the selection and the fabrication processes for designing the origami devices. New software is necessary for origami design. The military, medical, and space sectors are leading this research and development. As the concept is new, very few devices have been made with success. This paper outlines the development of origami design and describes the applications as well as the material selection and fabrication process.