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The strength of fixation of porous metal implants by the ingrowth of bone /Bobyn, John Dennis January 1977 (has links)
No description available.
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Porous bioceramic and biomaterial for bone implants /Chang, Hsuan-chen, January 2000 (has links)
Thesis (Ph. D.)--University of Texas at Austin, 2000. / Vita. Includes bibliographical references (leaves 286-298). Available also in a digital version from Dissertation Abstracts.
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The development of magnesium-based materials for orthopaedic applicationsWong, Hoi-man., 黃凱文. January 2011 (has links)
The currently used biomaterials for surgical implantation include stainless
steel, titanium and its alloys. However, due to the non-degradability and the
mismatch of the mechanical properties between these metallic implants and
human bone, there maybe a long-term adverse effect of inflammation or stress
shielding effect. This may lead to bone loss which brings with a higher risk of
implant failure. To avoid this problem, implants made of biodegradable
materials are the alternatives. Due to the poor mechanical properties of
biodegradable polymer especially for load-bearing area, biodegradable metal is
used instead. Magnesium is the potential candidate since it is degradable with
mechanical properties similar to human bone whilst magnesium ion is an
essential element to human bodies.
With the advantages of using magnesium for implantations, it can be
potentially used for fracture fixation implant and bone substitutes. However, its
rapid degradation and release of hydrogen gas may inhibit its use. Hence,
modification is required. In this project, plasma immersion ion implantation
and deposition (PIII&D) using aluminium oxide as the plasma source was
conducted on the magnesium alloys. The corrosion resistance properties of the
plasma-treated magnesium alloy were found to display significant
improvement in immersion test especially at early time points. The
plasma-treated sample was compatible with osteoblasts. Cells attached and
grew on the treated sample but not the untreated sample. The animal study
showed consistent results with the cell study, and there was a significant
increase in bone formation around the treated sample when compared to the
untreated sample.
The other potential application of magnesium is its usage as a bone
substitute. Due to the limitations of autografts and allografts, synthetic bone
substitutes are developed. The ideal bone substitutes should have similar
properties to those found with autografts. However, no such bone substitutes
presently exist; hence, a novel hybrid material is fabricated in this project
through the addition of magnesium granules into a biodegradable polymer
polycaprolactone (PCL). The immersion test showed that an apatite layer
composed of magnesium, calcium, phosphate and hydroxide was formed on the
hybrids but not on pure PCL, which suggested that the hybrids were
osteoinductive and osteoconductive. The compression test showed that the
mechanical properties were enhanced with the incorporation of magnesium
granules into pure PCL and were still maintained after 2 months of immersion.
Osteoblasts grew well on the PCL-Mg hybrids. The addition of smaller
amounts of magnesium granules (0.1g PCL-Mg) resulted in higher ALP
activity and up-regulation of different bone markers when compared to the
pure PCL. Finally, the animal studies showed that more new bone formation
was found around the 0.1g PCL-Mg hybrids especially at early time points,
which suggested that the healing time could be shortened.
In conclusion, fracture fixation implants and novel bone substitutes based
on magnesium were developed in this project. The aluminium oxide coating
was able to improve the corrosion resistance properties of magnesium alloy by
suppressing the release of magnesium ions. The PCL-Mg hybrids were found
to be biodegradable, biocompatible, osteoconductive, osteoinductive and
mechanically matched to human bone properties. / published_or_final_version / Orthopaedics and Traumatology / Doctoral / Doctor of Philosophy
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Antibacterial properties and biocompatibility of novel peptide incorporated titanium alloy biomaterials for orthopaedic implantsYeung, Che-yan, 楊芷茵 January 2010 (has links)
published_or_final_version / Orthopaedics and Traumatology / Master / Master of Philosophy
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The strength of fixation of porous metal implants by the ingrowth of bone /Bobyn, John Dennis January 1977 (has links)
No description available.
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The effect of surface roughness and a collar on fixation of cemented femoral stems in vivo / by Scott Andrew Brumby.Brumby, Scott Andrew January 1996 (has links)
Bibliography: leaves 193-206. / xiii, 206 leaves : ill. (chiefly col.) ; 30 cm. / Title page, contents and abstract only. The complete thesis in print form is available from the University Library. / This thesis investigates the effect of femoral stem surface roughness and a collar on the fixation of cemented hip hemi-arthroplasty femoral stems in an in vivo sheep model up to nine months following implantation. Plain radiography, micromotion between prosthesis and bone during mechanical testing and histology are used. / Thesis (Ph.D.)--University of Adelaide, Dept. of Orthopaedics and Trauma, 1997?
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A comparison of modeling techniques using the finite element method to determine local displacements in a human hip /Kinney, Timothy. January 2007 (has links)
Thesis (M.S.)--University of Missouri-Columbia, 2007. / The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on April 14, 2008) Includes bibliographical references.
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Measurement and analysis of surface topography over multiple length scales application to titanium bone implants /Sosale, Guruprasad. January 1900 (has links)
Thesis (M.Eng.). / Written for the Dept. of Mechanical Engineering. Title from title page of PDF (viewed 2008/01/14). Includes bibliographical references.
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Anti-bacteria plasma-treated metallic surface for orthopaedics useLeung, Kit-ying, January 2008 (has links)
Thesis (M. Phil.)--University of Hong Kong, 2009. / Includes bibliographical references (leaves 124-155) Also available in print.
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Biocompatibility of osteoblast cells on titanium implantsSomayajula, Dilip Ayyala. January 2008 (has links)
Thesis (M.S.)--Cleveland State University, 2008. / Abstract. Title from PDF t.p. (viewed on May 8, 2008). Includes bibliographical references (p. 72-76). Available online via the OhioLINK ETD Center. Also available in print.
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