Thesis (Ph. D.)--Oregon State University, 2007. / Includes bibliographical references (leaves 113-116). Also available online (PDF file) by a subscription to the set or by purchasing the individual file.

Thesis (Ph. D.)--Oregon State University, 2007. / Includes bibliographical references (leaves 113-116).

Ninety-three publications have been presented from the last 22 years. This body of work represents an opus of publications from the author's own medical qualification, in 1980, until the present day. They vary from short abstracts representing research presentations at scientific meetings through to major multi-centre international studies and significant contributions to medical texts. They are accompanied by an overview, which details original contributions to medical knowledge and superior methodology, reinforced by calculation of a citations index, which demonstrates the impact of such research on the medical community. The overview has chosen to collate the output into four main clusters of which Haemophilia represents the largest numerically, with forty-seven contributions, and the most significant scientifically. The other three groups represent Infection, including HIV and Hepatitis, Trauma and its sequelae, and General Surgery and Orthopaedics. Contributions on the issues of surgery on HIV positive Haemophilic patients, the more general problems surrounding surgical intervention in Haemophilia, and the natural history of Orthopaedic pathology in these patients has been the area where it is felt the most significant contribution has been made. Papers have been published demonstrating the generally positive clinical and economic outcomes following different forms of joint replacement in Haemophilia. However, the markedly increased infection risks following joint replacement in HIV positive Haemophilic patients has been highlighted in the largest paper published on the subject, combining the results from many different countries. In contrast, by access to historical laboratory specimens, it has been shown that Orthopaedic surgical interventions have not adversely affected the natural history of HIV in terms of immune competence. A number of papers have been published on the subject of the natural history of ankle arthropathy in Haemophilia - an area under investigated in the past. A critical review of accepted scoring systems in Haemophilia has been published with a more scientifically evaluated system suggested in its stead. The Infection section has developed from the initial interests in the problems encountered in Haemophilia. Further work has been undertaken evaluating protective gloves designed to minimise injury to staff during high risk procedures and the more general exposure to HIV and Hepatitis in general Orthopaedic practice. The Trauma section presents a number of varied papers in terms of publication type and subject matter. The randomised prospective paper on intertrochanteric fractures of the hip, demonstrating no advantage in outcome following a more technically difficult surgical procedure, is an important contribution to the iterature. The first paper published on the pathology demonstrated by CT following an initial shoulder dislocation has been a similarly influential publication - as demonstrated by its citation count. The final section on General Surgery and Orthopaedics provides a catholic collection of publications reflecting a number of surgical interests and career appointments. One paper from this group was particularly influential. It evaluated the outcomes of knee arthroscopy as a day case procedure and it was an mportant contribution at its time, as witnessed by its widespread acceptance as normal practice sixteen years later.

Many study designs are used to provide the answers needed to further the care of orthopedic oncology patients. Underlying these differing study designs, are different data sets. The data sets vary in their size and scope, from single center to population-based, and from provincial to international. They vary in their follow-up time, from years to decades. They vary in the variables included, the fidelity and precision of each variable, and the granularity of detail. This thesis explores the use of population-based studies as a source of data on orthopedic oncology patients, and provides two studies as an example. We make use of the large administrative data collected from every soft tissue sarcoma (STS) patient in Ontario over 23 years by the Institute of Clinical Evaluative Sciences (ICES) to answer two questions only possible with population-based studies. Using this large cohort (n=8,896) we provide for the first-time answers to 1) Given the multidisciplinary treatment of sarcoma patients, how are Ontario sarcoma patients being treated in our universal healthcare system, and, have treatment strategies changed over the past 10 years? 2) What are the long-term survival outcomes of Ontario sarcoma patients? Do these outcomes differ for rural or low-income patients? These studies have engendered international collaborations which are also described. Overall, this thesis explores research questions that are possible to address with population-based data. Through two studies, we aim to provide accurate and clinically useful information that can hopefully be used to better the outcomes of sarcoma patients, both in Ontario and internationally. / Thesis / Master of Science (MSc)

Objective — To describe the vascular distribution pattern of contrast medium during intraosseous regional perfusion (IORP) of the distal portion of the forelimb in horses. Sample Population — 13 cadaver forelimbs from 12 horses without vascular or orthopedic disease of the distal forelimb. Procedure — Serial lateromedial radiographs were taken of 10 heparinized cadaver distal forelimbs at 0, 1, 2, 6, 15, and 30 minutes during IORP of the third metacarpal bone (MCIII) using iodinated contrast medium and a tourniquet placed over the proximal MCIII. Vascular regions of interest (ROI) were created for each radiograph. Reviewers identified presence or absence of contrast in each ROI. This information was summarized to identify vessel-filling patterns over time. Vessel identification was verified using computed tomography angiography and latex perfusion studies on separate cadaver distal forelimbs. Results — During IORP, contrast medium filled the medullary cavity of the MCIII, exited via trans-cortical vessels and diffused distally to the remaining arteries and veins of the limb, distal to the tourniquet. Maximum vessel and soft tissue opacification occurred in most specimens at 6 and 30 minutes, respectively. Serial radiography vessel patterns matched those of CT images and dissected specimens. Conclusions and Clinical Relevance — Intraosseous regional perfusion provides a repeatable pattern of vascular distribution in the distal portion of the equine forelimb. This is the first documentation of arterial perfusion using this technique. Previous reports indicate that IORP only delivers medications to the venous vessels of the perfused limb. Maximum soft tissue perfusion was observed at 30 minutes. / Master of Science

SAMMANFATTNING                                                                                                       Bakgrund Den ortopediska skadan kan för patienten vara en mycket smärtsam process och orsaka långvarigt lidande. Detta ställer höga krav på sjuksköterskans kompetens som utifrån patientens individuella behov måste tillämpa en god personcentrerad omvårdnad. Syfte Syftet med denna litteraturstudie är att undersöka patientens upplevelse av omvårdnadsåtgärder vid ortopediska skador, samt få en ökad förståelse för betydelsen av personcentrerad omvårdnad vid dessa åtgärder. Metod Då författarna valde att använda redan publicerad forskning användes litteraturstudie som metod. Artiklarna söktes fram i databaserna Cinahl och Pubmed med sökorden orthopaedic, patient, experience, interview. Efter noggrann granskning och värdering av artiklarna inkluderades totalt elva artiklar. Resultat I resultatet redovisas fyra kategorier; information, stöd från vårdpersonal, främja delaktighet och smärtlindring, som för patienten fick en stor betydelse för upplevelsen av omvårdnadsåtgärder vid ortopediska skador. Slutsats Denna studies resultat visar att det utifrån patienternas upplevelser finns ett behov av förbättring. Följaktligen kan vårdpersonalen förbättra sitt utförande av ortopediska omvårdnadsåtgärder, och därmed tillämpa en personcentrerad omvårdnad.     Nyckelord: orthopedic, patient, experience, nursing. / ABSTRACT Background The orthopaedic injury can be a painful experience and cause long-time suffering. This put up for high requirements for the nurse who needs to apply a person-centered care. The aim The aim of the study was to investigate the patient´s experience of provided care when having an orthopedic injury. The second purpose was to obtain knowledge about the meaning of person-centered care. Method A Literature review was used as method though the writers wanted to use already published material. The search of the articles was made in the databases Cinahl and PubMed with the words orthopedic, patient, experience interview. After examining the articles a total of 11 articles were included. Result The results revealed four categories; information, support from the medical staff, participation and alleviation of pain. These categories had a big impact of the patient´s experience of the provided care they were given. Conclusion In this study the result showed that the patients’ experiences found a need of improvement in the work of the nursing-staff. Therefore the nursing-staff can improve their orthopedic care and apply a person-centered care. Keywords: orthopedic, patient, experience, nursing.

No description available.

Poster exhibited at GPSC Student Showcase, February 24th, 2016, University of Arizona.

Thesis (M.S.)--Auburn University, 2007. / Abstract. Includes bibliographic references (ℓ. 132-133)

Thesis (M.S.E.S.)--University of Toledo, 2008. / Typescript. "Submitted as partial fulfillments of the requirements for The Master of Science degree in Exercise Science." "A thesis entitled"--at head of title. Bibliography: leaves 42-46.