Thesis (M.S.)--University of Missouri-Columbia, 2004. / "Master of Science in Nutritional Science with minor in Statistics"--T.p. Typescript. Vita. Includes bibliographical references (leaves 127-146). Also available on the Internet.

Thesis (M.S.)--University of Missouri-Columbia, 2004. / "Master of Science in Nutritional Science with minor in Statistics"--T.p. Typescript. Vita. Includes bibliographical references (leaves 127-146). Also available on the Internet.

The objective of this study was to investigate the extent to which vitamin D and K are associated with bone health in pediatric cystic fibrosis (CF) patients. We hypothesized that: (1) the prevalence of vitamin D and K deficiencies would be high despite routine vitamin therapy, (2) bone health would be reduced and (3) vitamin K and D status would be associated with bone health. / Our results showed poor bone mineral mass in these CF children despite mild disease and good nutritional status. Neither vitamin K nor D was a predictor of bone health but weight and height Z-scores, fat-free mass, physical activity and lung function were all consistent predictors. / These results indicate that nutritional status as well as physical activity are key determinants of bone health in CF children and offer a unique opportunity in the prevention of CF-related bone disease. Further vitamin intervention research needs to be done in this population.

No description available.